Systematic Approach to Evaluation of Mouse Mutations: 1st Edition (Hardback) book cover

Systematic Approach to Evaluation of Mouse Mutations

1st Edition

Edited by John P. Sundberg

CRC Press

216 pages

Purchasing Options:$ = USD
Hardback: 9780849319051
pub: 1999-07-23
eBook (VitalSource) : 9780429125348
pub: 1999-07-23
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Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. Systematic Approach to Evaluation of Mouse Mutations includes information on medical photography, grafting procedures, how to map the genes and evaluate the special biological characteristics of the mice.


"The Jackson Lab crew, with assists from other contributors, have put together a reference for scientists, mouse geneticists, managers and lab animal veterinarians. … This new edition is a valuable reference for those involved with transgenic mice and mice colonies where specific mutations are maintained as research models."

-Mark Klinger in Laboratory Animal Practitioner

Table of Contents

Mouse Colony Establishment-Dawnalyn Boggess and John P. Sundberg

Determining the Genetic Basis of a New Trait-Xavier Montagutelli

Computerized Colony Record Keeping-David Larkin

Medical Record Keeping for Project Analysis-Beth A. Sundberg and John P. Sundberg

Necropsy Methods for Laboratory Mice. Biological Characterization of a New Mutation-Melissa J. Relyea, James Miller, Dawnalyn Boggess, and John P. Sundberg

Photography of Mutant Laboratory Mice-John P. Sundberg and James Miller

Comparative Pathology and Animal Model Development-John P. Sundberg and Lloyd E. King, Jr.

Kinetics and Morphometrics-Richard S. Smith, Greg Martin and Dawnalyn Boggess

Ultrastructural Evaluation of Mouse Mutations-Leslie Bechtold

Immunohistochemical and Immunofluoresence Methods-Melissa J. Relyea, John P. Sundberg, and Jerry M. Ward

Radiolabeled cRNA and In Situ Hybridization-Diane S. Keeney

In Situ Hybridization with Non-Radiolabeled Probes-Brian J. Limberg and Charles C. Bascom

Repositories of Mouse Mutations and Inbred, Congenic and Recombitant Inbred Strains-Muriel T. Davisson and John Sharp

About the Authors/Editor

John P. Sundberg, Dawnalyn Boggess

About the Series

Research Methods For Mutant Mice

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Immunology
MEDICAL / Research
SCIENCE / Life Sciences / Neuroscience