Textbook of Pleural Diseases: 3rd Edition (Pack - Book and Ebook) book cover

Textbook of Pleural Diseases

3rd Edition

Edited by Richard W. Light, Y C Gary Lee

CRC Press

651 pages | 323 Color Illus.

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The Second Edition of this book was the Winner of the First Prize (Respiratory Category) at the British Medical Association Medical Book Awards. 

Textbook of Pleural Diseases is a comprehensive reference that covers both the basic and clinical science on pleural diseases. Building on the highly respected previous editions, it includes a detailed basic science section for enhanced understanding of both the physiological and pathophysiological mechanisms that underpin diseases of the pleura.

The clinical sections are written in a uniform style and include the definition, epidemiology, etiology, pathogenesis, clinical presentation, investigations, treatments, and possible complications for various pleural diseases. Other clinical chapters discuss both familiar and less common disease aspects.

Five new chapters have been added covering new technologies in the clinical management of pleural diseases, procedural complications and safety measures, and the setting up of a pleural practice. The remaining chapters have been substantially updated. About a third of the 50 chapters in this edition are written by new expert authors providing a fresh view and reflecting the expansion of knowledge in the field.

Each chapter includes a bullet-point summary, and published management guidelines are included where relevant. Also included is a "Key Points" section in each chapter that highlights patient management, making this an indispensable reference for pulmonary physicians, internists, thoracic surgeons and trainees worldwide.


"This is a classic that has been updated with an excellent third edition. The updated chapters and new chapters encompass the scope of our current understanding of pleural disease. This is an important book for practitioners and scientists in the field and should be in every academic library. The website offers many advantages and is a welcome addition." - 4 stars (93/100), Michael Bates, MD (Ochsner Medical Center), Doody's Book Review Service

Table of Contents

Pleural Diseases: Historic Perspective

Gian Franco Tassi and Gian Pietro Marchetti


Pleural Embryology and Gross Structure, Circulation, Lymphatics, and Nerves

Rob J. Hallifax and Najib M. Rahman

Mesothelial Cells and Pleural Immunology

Steven E. Mutsaers, Marie-Claude Jaurand, Y. C. Gary Lee, and Cecilia M. Prêle

Normal Physiological Fluid and Cellular Contents

Marc Noppen

Fluid and Solute Exchange in Normal and Disease States

V. Courtney Broaddus

Pleural Inflammation

Jason S. Zolak and Veena B. Antony

Pleural Fibrosis

Torry A. Tucker, Andrey A. Komissarov, Galina Florova, Sreerama Shetty, and Steven Idell

Genetics of Mesothelioma

Dean A. Fennell and Sara Busacca

Transcriptomics and Proteomics in Pleural Diseases

Joost P. Hegmans, Lysanne A. Lievense, and Joachim G. Aerts

Pleural Pharmacokinetics

Natalia Popowicz and Brad Sparling

Experimental Models: Pleural Disease

Georgios T. Stathopoulos, Y.C. Gary Lee, and Bruce W.S. Robinson


Approach to Patients with Pleural Diseases

Oliver Bintcliffe and Nick Maskell

Pleural Fluid Analysis

John E. Heffner

Pleural Manometry

David Feller-Kopman

Radiology: Diagnostic

Fergus V. Gleeson

Radiology: Interventional

Iara Maria Sequeiros and Anthony Edey

Radiology: Pleural Ultrasound

Coenraad F.N. Koegelenberg and Andreas H. Diacon

Radiology: Nuclear Imaging

Roslyn Francis and Anna Nowak

Pleural Histology

Philip T. Cagle and Timothy Craig Allen

Pleural Fluid Cytology

Amanda Segal, Marais Combrinck, and Siaw Ming Chai

Effusions from Cardiovascular Diseases

José M. Porcel and Richard W. Light

Effusion from Malignant Causes

Rajesh Thomas, Ioannis Kalomenidis, James Jett, and Y.C. Gary Lee

Effusions from Infections: Parapneumonic Pleural Effusion and Empyema

John P. Corcoran and Najib M. Rahman

Effusions from Infections: Tuberculosis

Luke C. Strnad, Claudia M. Denkinger, and Madhukar Pai

Effusions from Atypical Infections

Lisete R. Teixeira and Francisco S. Vargas

Effusions Due to Lymphatic Disruption

J. Terrill Huggins and Peter Doelken

Effusions in Immunocompromised Hosts

Rosemary Adamson and David R. Park

Effusions from Connective Tissue Diseases

Stavros Anevlavis and Demosthenes Bouros

Effusions Caused by Drugs

Vasileios Skouras and Ioannis Kalomenidis

Effusions after Surgery

Oner Dikensoy and Richard W. Light

Effusions from Hepatic Hydrothorax

José Castellote and Xavier Xiol

Effusions Caused by Gastrointestinal Disease

David Hsia and Ali I. Musani

Effusions Associated with Gynecologic and Obstetric Conditions

Benjamin C.H. Kwan and Richard W. Light

Other Uncommon Pleural Effusions

Craig E. Daniels and Jay H. Ryu

Solitary Fibrous Tumors of the Pleura

Marc De Perrot and Olaf Mercier

Undiagnosed Pleural Effusions

A. Christine Argento and Momen M. Wahidi

Asbestos-Related Pleural Diseases

Fraser J.H. Brims and A.W. Musk


Marc Van Lanen and Paul Baas

Spontaneous Pneumothorax

Paul E. Van Schil, Dragan Subotic, Chantal Vandenbroeck, Jeroen M. Hendriks, Marjan Hertoghs, and Patrick Lauwers

Non-Spontaneous Pneumothorax

Demondes Haynes and Michael H. Baumann

Pleural Effusions in Pediatric Patients

Esmeralda Morales and Elizabeth Perkett

Pleural Procedural Complications and Safety Measures

Luke Garske and Claire Tobin

Drainage Techniques

Henri Colt


Helen E. Davies and Y.C. Gary Lee

Tunneled Pleural Catheters

Alex Chee, Paul Maceachern, David R. Stather, and Alain Tremblay

Medical Thoracoscopy

Pyng Lee and Philippe Astoul

Surgery for Pleural Diseases

Lawrence Okiror and Loic Lang-Lazdunski

Gene Therapy in Pleural Diseases

Edmund K. Moon, Steven M. Albelda, and Daniel H. Sterman

Setting up a Pleural Practice

Rahul Bhatnagar and Nick Maskell

Future Directions in Pleural Disease

Y.C. Gary Lee and Richard W. Light

About the Editors

Edited by

Richard W. Light, MD, FCCP, professor of medicine, Vanderbilt University, Nashville, Tennessee, USA, and Gaziantep University, Turkey

Y. C. Gary Lee, MBChB, PhD, FRACP, FRCP, FCCP, professor of respiratory medicine, University of Western Australia; director of pleural services, Sir Charles Gairdner Hospital; and Queen Elizabeth II Medical Centre, Perth, Australia

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Pulmonary & Thoracic Medicine