312 pages | 8 Color Illus. | 128 B/W Illus.
For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from this course, the perennially bestselling Textbook of Receptor Pharmacology has presented in-depth coverage of this rapidly expanding area of research. This third edition continues to combine current understanding of classical quantitative pharmacology and drug-receptor interactions with the basics of receptor structure and signal transduction mechanisms, providing an integrated analysis of the mechanisms of drug action at membrane receptors.
The hallmark of this popular text is the uniting of four major approaches to the study of receptors:
Maintaining the second edition’s focus on cell membrane receptors and the immediate signal transduction events at the membrane, this edition includes updated chapters on receptor structure and signal transduction by G-proteins and tyrosine kinases as well as enhancements to the quantitative treatment of drug-receptor interactions. Several chapters contain problems and worked-out solutions, giving students the ability to test their comprehension of the material. Hundreds of diagrams and figures further enhance the text.
A time-saving resource and comprehensive learning tool, Textbook of Receptor Pharmacology, Third Edition carries on the tradition of providing in-depth, up-to-date coverage of this critical area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.
" … very well written and informative. This edition updates and refines earlier versions of what is an excellent, interesting, and very informative text on receptor pharmacology, but what else would one expect with contributions from such giants in the discipline? This book is ideal for budding pharmacologists and cell physiologists, both at the undergraduate and postgraduate level, who have an interest in receptor structure and function â€¦ would also be of value to students and academics of pharmacy, physiology, medicinal chemistry, and related disciplines."
Classical Approaches to the Study of Drug-Receptor Interactions, Donald H. Jenkinson
Molecular Structure of Receptors
Structure and Function 7-TM G-Protein Coupled Receptors, Alasdair J. Gibb
The Structure of Ligand-Gated Ion Channels, Jan Egebjerg
Molecular Structure of Receptor Tyrosine Kinases, IJsbrand Kramer and Michel Laguerre
Ligand-Binding Studies of Receptors
Direct Measurement of Drug Binding to Receptors, Dennis G. Haylett
Transduction of the Receptor Signal
Receptors Linked to Ion Channels: Mechanisms of Activation and Block, Alasdair J. Gibb
G-Proteins, David A. Brown
Signal Transduction through Protein Tyrosine Kinases, IJsbrand Kramer and Elisabeth Genot
Receptors as Pharmaceutical Targets
Receptors as Pharmaceutical Targets, James W. Black