A biofilm is a complex aggregation of microbes usually attached to a solid surface. Traditional studies of bacteria sometimes implied that microbes live as single organisms; it is now clear that in nature microbes usually live in co-operative groups attached to surfaces. This book, written by leading international scientists, presents an overview of the most recent and exciting new research into the mechanisms that underpin the biofilm mode of life. Essential reading for anyone interested in biofilms.
1. Introduction 2. The Biofilm Mode of Life 3. Do Not Fear Commitment: The Initial Transition to a Surface Lifestyle by Pseudomonads 4. The Biofilm Matrix: A Sticky Framework 5. Cyclic di-GMP as an Intracellular Signal Regulating Bacterial Biofilm Formation 6. N-Acylhomoserine Lactones, Quorum Sensing and Biofilm Development in Gram-Negative Bacteria 7. Signaling in Escherichia coli Biofilms 8. Peptide Signaling 9. Differentiation and Dispersal in Biofilms 10. Human Oral Multi-Species Biofilms: Bacterial Communities in Health and Disease 11. Biofilms as Refuge Against Predation 12. Biofilms on Plant Surfaces 13. Bacterial Biofilms on Fungal Surfaces