The Endothelium: Modulator of Cardiovascular Function, 1st Edition (Hardback) book cover

The Endothelium

Modulator of Cardiovascular Function, 1st Edition

By Thomas F. Luscher, Paul M. Vanhoutte

CRC Press

228 pages

Purchasing Options:$ = USD
Hardback: 9780367243326
pub: 2019-05-23

FREE Standard Shipping!


First published in 1990: The Endothelium: Modulator of Cardiovascular Function takes a comprehensive look at the role of the endothelium in cardiovascular control in health and disease. Experts offer detailed reviews on specific topics that address these roles of the endothelium: diffusion barrier, blood-brain barrier, regulator of capillary permeability, metabolic function (uptake and enzymatic destruction), conversion of vasoactive products, production of prostanoids, production and release of endothelium-derived relaxing factors, production of endothelium-derived contracting factors, production of coagulation factors, production of fibrinolytic factors, reticulo-endothelial function, role in atherosclerosis, and changes in function with aging and disease. This overview provides the reader with an update on the role of one of the most fascinating cells in cardiovascular biology. It focuses on the multiple functions of those cells and offers the first attempt to draw a parallel between these functions. Anyone studying the fields of physiology and pharmacology will benefit from this "must have" reference resource.


"…efficiently organized…This book is recommended to anyone who wants both a concise review and an authoritative reference on endothelial function. "

-Journal of Vascular Surgery

Table of Contents

1. Introduction 2. Methods to Study Endothelium-Dependent Responses 3. Endothelium-Derived Relaxing Factor 4. Other Relaxing Substances Released by the Endothelium 5. Production and Contracting Agents 6. Local Regulation of Endothelium-Dependent Responses 7. Neurohumoral Regulation 8. Heterogeneity and Chronic Modulation 9. Disease 10. Therapeutic Implications 11. References

About the Authors

Thomas F. Luscher, M.D., is Associate Consultant in Cardiology and Assistant Professor at the Department of Medicine and head of the Laboratory of Vascular Research at the Department of the University Hospital, Basel.

Paul Michel Vanhouette, M.D., Ph.D., is the Director of the Center for Experimental Therapeutics at the Department of Medicine of Baylor College, in Houston.

About the Series

Routledge Revivals

Are there elusive titles that you need and have been trying to source for years but thought that you would never be able to find?

Well this may be the end of your quest – here is a fantastic opportunity for you to discover past brilliance and purchase previously out of print and unavailable titles by some of the world’s most eminent academic scholars.

Drawing from over 100 years of innovative, cutting-edge publishing, Routledge Revivals is an exciting programme whereby key titles from the distinguished and extensive backlist of the many acclaimed imprints associated with Routledge will be re-issued.

The programme draws upon the illustrious backlists of Kegan Paul, Trench & Trubner, Routledge & Kegan Paul, Methuen, Allen & Unwin and Routledge itself.

Routledge Revivals spans the whole of the Humanities and Social Sciences, and includes works by some of the world’s greatest thinkers including Emile Durkheim, Max Weber, Simone Weil, Martin Buber, Karl Jaspers and Max Beloff.

If you are interested in Revivals in the Behavioral Sciences, please visit

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Cardiology
MEDICAL / Pharmacology