This book is devoted to the pathophysiology of the microcirculation, an intensely studied area of the circulatory system. Featuring contributions from 29 top investigators in the field, the book begins with an introduction to the general structure of the normal microvascular system, with special emphasis on the characteristics of blood vessel segments collectively comprising the system. Significant areas covered in the book include angiogenesis, neoplasias, hypertension, shock, ischemia/reperfusion, diabetes, immunologic injury, and thermal injury. It also covers the effects of aging and environmental factors on the microcirculation-topics not often examined in depth. More than 80 figures and tables illustrate key concepts throughout the book.
Anatomy of the Microvascular System (R.S. McCuskey and M.A. Krasovich). Coronary Angiogenesis and Its Control (H.J. Granger, J.R. Hawker, Jr., C.J. Meininger, D.C. Zawieja, L.E. Czisny, and M. Ziche). Neoplasia (R.F. Nicosia and G.G. Pietra). Hypertension (R.L. Prewitt, D.H. Wang, and M.A. Hill). Circulatory Shock (L.B. Hinshaw and T.E. Emerson, Jr.). Ischemia/Reperfusion Injury (P. Kubes, P.R. Kvietys, and D.N. Granger). Diabetic Microangiopathy (R.J. Korthuis, S.P. Fuselier, and S.N. Jerome). Immunologic Injury (D.J. Dzielak, R.L. Hester, and J.P. Granger). Thermal Injury (D.L. Traber, C.W. Lentz, C.S. Cox, Jr., L.D. Traber, and D.N. Herndon). Adjustments Associated with the Aging Process (D.R. Richardson). Impact of Environmental Factors (K.S. Ramos and R.C. Bowes, III). Index.