The Science of Phototherapy: 1st Edition (Hardback) book cover

The Science of Phototherapy

1st Edition

By Leonard I. Grossweiner

CRC Press

227 pages

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Hardback: 9780849349805
pub: 1994-09-22
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The Science of Phototherapy reviews the current status of established and emerging phototherapies, including recent information about the mechanisms of action. The major topics are developed from basic principles in order to be most useful to readers with different backgrounds. The book describes the operation of phototherapy instrumentation, including conventional and laser light sources, photodetectors, radiometers, and optical fibers and features a comprehensive treatment of tissue optics ranging from basic principles to clinical applications. The applications of phototherapy to light dosimetry, optical diagnosis, and laser surgery are further developed with worked examples, and the more quantitative topics are explained with the use of illustrations. The book includes an extensive bibliography.


"The author, himself a physicist, does an admirable job in combining the variety of detailed information currently available on the science and technology of phototherapy…thus providing a concise general reference."

-J. Hagekyriakou in Cancer Forum, Volume 19, Number 3, November 1995

Table of Contents

An Overview of Phototherapy

Classical Description of Light Interactions with Matter

The Nature of Light

Macroscopic Optical Phenomena

Light Photons

Optical Radiometry

Molecular Description of Light Interactions with Matter

The Photoelectric Effect

Molecular Structure and Energetics

Photochemical Reactions



Conventional Light Sources


Radiometric Instrumentation

Optical Components

Tissue Optics

Fundamentals of Tissue Optics

Tissue Optic Theories

Time-Dependent Tissue Optics

Monte Carlo Simulation

Applications of Tissue Optics to Light Dosimetry in Phototherapy

Light Dosimetry Modeling

Optical Methods of Diagnosis and Imaging

Laser Interactions with Tissue

Laser-Tissue Interactions

Tissue Heating by Laser Radiations

Laser Ablation of Tissues

Photodynamic Therapy

Clinical Implementation of PDT

PDT Drugs

PDT Action Mechanism

Light Delivery and Dosimetry for PDT

The Current Status of PDT

UV Phototherapy of Skin Disease

UV-B Phototherapy

UV-A Plus Psoralen Phototherapy

Extracorporeal Photophoresis

Phototherapy of Hyperbilirubinemia

Bilirubin Metabolism

Action Mechanism of the Phototherapy

Light Sources for Phototherapy of Hyperbilirubinemia

Emerging and Speculative Phototherapies

New Approaches to Photochemotherapy


Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Dermatology
MEDICAL / Oncology
MEDICAL / Radiology & Nuclear Medicine