This volume offers the most comprehensive presentation available on metal toxicology. It discusses not only metals but also the toxic endpoints, such as neurotoxicity, renal toxicity, and cancer induction. Chapters are written by experts in their respective fields, focusing on carcinogenesis and human exposures and highlighting the major aspects and issues of toxicity in general.
Table of Contents
GENERAL AND CLINICAL ASPECTS, RISK ASSESSMENT, AND GENOTOXICITY OF METALS Monitoring, Environmental, and Health Risk Assessments, An Introduction to Monitoring and Environmental and Human Risk Assessment of Metals, Monitoring and Assessment of Metal Contaminants in the Air, Assessment of Ecological and Health Effects of Soil-Borne Trace Elements and Metals, Assessment of Metals in Drinking Water With Specific References to Lead, Copper, Arsenic, and Selenium, Risk Assessment of Metals, Techniques Employed for the Assessment of Metals in Biological System, Concepts on Biological Markers and Biomonitoring for Metal Toxicity, Bioresponses and Reactivities to Metal Toxicity An Introduction to Bioresponses and Reactivities of Metals, Determinants of Reactivity in Metal Toxicity, Metals and Biological Membranes, Interactions Between Glutathione and Mercury in the Kidney, Liver, and Blood, The Role of General and Metal-Specific Cellular Responses in Protection and Repair of Metal-Induced Damage: Stress Proteins and Metallothioneins, Metal-Metal Interactions, Carcinogenesis and Genotoxicity of Metals Part A: Carcinogenicity and Genotoxicity of Specific Metals An Introduction to Metal Toxicity and Carcinogenicity of Metals, Carcinogenicity and Genotoxicity of Chromium, The Carcinogenicity of Arsenic, Cadmium Carcinogenicity and Genotoxicity, Mechanisms of Nickel Genotoxicity and Carcinogenicity, Carcinogenicity and Genotoxicity of Lead, Beryllium, and Other Metals, Part B: Selected Concepts in Metal Carcinogenesis An Introduction to Selected Concepts in Metal Carcinogenesis, Metal Interactions in Chemical Carcinogenesis, Oxidative DNA Damage in Metal-Induced Carcinogenesis, Metal-Induced Gene Expression and Neoplastic Transformation,Clinical Aspects of Metal Toxicity An Introduction to Clinical Aspects of Metal Toxicity, Minamata Disease and Other Mercury Syndromes, Itai-Itai Disease and Health Effects of Cadmium, Genetic Disorders of Copper Metabolism, Alzheimer's Disease and Other Aluminum-Associated Health Conditions, Current Status of Childhood Lead Exposure at Low Dose, Neurological Aspects in Human Exposure to Manganese, Health Effects of Arsenic, Toxicity of Bismuth and Its Compounds, Human Exposure to Lithium, Thallium, Antimony, Gold, and Platinum, Cobalt and Nickel Induced Hard Metal Asthma, Aspects on Health Risks of Mercury from Dental Amalgams, Chelation Therapies for Metal Intoxication
Louis W. Chang