This book provides an overview of the state of the art in pharmaceutical applications of UV-VIS spectroscopy. This book presents the fundamentals for the beginner and, for the expert, discusses both qualitative and quantitative analysis problems. Several chapters focus on the determination of drugs in various matrices, the coupling of chromatographic and spectrophotometric methods, and the problems associated with the use of chemical reactions prior to spectrophotometric measurements. The final chapter provides a survey of the spectrophotometric determination of the main families of drugs, emphasizing the achievements of the last decade.
Table of Contents
1. The Measurement of Light Absorption - and Reflection 2. Qualitative Analysis: Relationship Between the Structure and Spectra of Pharmaceutical Compounds 3. Quantitative Analysis Based on Natural Light Absorption 4. Combination of Spectrophotometric Methods with Chromatographic Techniques 5. Spectrophotometric Methods Based on Chemical Reactions 6. Chemical and Spectroscopic Characterization of Derivatization Reactions 7. Difference Spectrophotometry 8. Spectrophotometric Determination of Pharmaceuticals in Various Matrices 9. Spectrophotometric Analysis of Some Important Groups of Drug Compounds