This book is for the guidance of those wishing to use stained cultures for virus studies.In this manual, sufficient illustrations are presented that may not be otherwise readily available to the reader and indicate the wide range of cytopathic changes. However, it has been necessary to limit the size of the pictures to a minimum - enough to convince the reader that the technique can be of great practical value for the recognition of many different viruses.

    1. Introduction 2. General Conditions of Cytopathic Changes 3. Preparation of Cell Cultures for the Study of Cytopathic Changes 4. Fixatives and Stains 5. Cytopathic Changes Affecting Mainly the Cytoplasm 6. Cytopathic Changes Affecting Mainly the Nucleus 7. Cytopathic Changes Affecting Both Cytoplasm and Nucleus 8. Infection by More Than One Virus 9. Identification of Some Contaminants

    Biography

    Hubert H. Malherbe, Margaret Strickland-Cholmley