© 2013 – CRC Press
462 pages | 43 B/W Illus.
Vitamin D insufficiency/deficiency is a worldwide, public health problem in both developed and developing countries. Rickets among infants has reemerged. Low levels of vitamin D are associated with increased risk and mortality from cancer. At the same time, the beneficial effects of vitamin D on a host of conditions have recently been discovered. Focusing on areas not extensively covered in other comparable books, Vitamin D: Oxidative Stress, Immunity, and Aging highlights the most recent research findings on the impact of this nutrient in oxidative stress, immunity, and aging.
A state-of-the-art compilation of essential information, this book explores:
This book represents an important contribution toward understanding the mechanisms by which vitamin D promotes health, increasing awareness of the importance that vitamin D plays during development, at birth, and throughout the aging process. It is a valuable reference for researchers in academia, nutrition, medicine, and industry.
Vitamin D: An Overview
Vitamin D: A Fountain of Youth in Gene Regulation; Peter W. Jurutka, G. Kerr Whitfield, Ryan Forster, Shane Batie, Jamie Lee, and Mark R. Haussler
Vitamin D Receptor: Genomic and Epigenomic Effects; Prashant K. Singh and Moray J. Campbell
Vitamin D Analogs and Their Clinical Uses; Glenville Jones
Extrarenal CYP27B1 and Vitamin D Physiology; Martin Hewison
Vitamin D and Oxidative Stress; Huei-Ju Ting and Yi-Fen Lee
Vitamin D3 Upregulated Protein 1 (VDUP1): Roles in Redox Signaling and Stress-Mediated Diseases; Dong Oh Kim, Hyun Woo Suh, Haiyoung Jung, Young Jun Park, and Inpyo Choi
Vitamin D and Its Role in Photoprotection of the Skin; Clare Gordon-Thomson, Wannit Tongkao-on, and Rebecca S. Mason
Vitamin D and Adipose Tissue: 1α, 25-Dihydroxyvitamin D3 (Calcitriol) Modulation of Energy Metabolism, Reactive Oxygen Species, and Inflammatory Stress; Antje Bruckbauer and Michael B. Zemel
Membrane Receptors for Vitamin D Metabolites and the Role of Reactive Oxygen Species; Ramesh C. Khanal and Ilka Nemere
Immunity and Disease
Vitamin D and Human Innate Immunity; Eun-Kyeong Jo, Dong-Min Shin, and Robert L. Modlin
Vitamin D and Autoimmune Disease; Colleen E. Hayes, Corwin D. Nelson, and Justin A. Spanier
Vitamin D: Anti-Inflammatory Actions to Prevent and Treat Diseases; Jun Sun
Vitamin D and Infection; Jim Bartley and Carlos A. Camargo, Jr.
Potential Role of Vitamin D and Fibroblast Growth Factor 23–Klotho System in Aging; Nasimul Ahsan, Syed K. Rafi, Beate Lanske, and Mohammed S. Razzaque
Vitamin D and Cardiovascular Disease; Jared P. Reis and Pamela L. Lutsey
Vitamin D, Aging, and Chronic Diseases; Pentti Tuohimaa
Vitamin D: Defending the Aging Nervous System; Cédric Annweiler