Danko D. Georgiev Author of Evaluating Organization Development
FEATURED AUTHOR

Danko D. Georgiev

Principal Investigator
Institute for Advanced Study

Danko D. Georgiev earned his M.D. from Medical University of Varna, Bulgaria, graduating summa cum laude in 2004, and his Ph.D. in Pharmaceutical Sciences from Kanazawa University, Japan, in 2008 for his research in the area of neuronal differentiation. Dr. Georgiev currently conducts theoretical and applied interdisciplinary research across a number of disciplines including quantum physics, quantum chemistry, neuroscience, cognitive science, information science and mathematics.

Biography

Danko D. Georgiev earned his M.D. from Medical University of Varna, Bulgaria, graduating summa cum laude in 2004, and his Ph.D. in Pharmaceutical Sciences from Kanazawa University, Japan, in 2008 for his research in the area of neuronal differentiation. He has worked as an anesthesiologist at the Naval Hospital, Varna, and was also a researcher in the Department of Psychiatry and Neurobiology at Kanazawa University, where he studied the molecular alterations in the cerebral cortex of subjects with schizophrenia. He held a two-year JSPS Postdoctoral Fellowship awarded by the Japan Society for the Promotion of Science, and was a short-term visiting scholar at the Department of Psychiatry, University of Pittsburgh. He was then a postdoctoral associate in the Department of Environmental and Occupational Health, University of Pittsburgh, where he performed cutting-edge research on the pathogenesis and treatment of Alzheimer's disease. Dr. Georgiev is currently a principal investigator at the Institute for Advanced Study, Varna, Bulgaria. He has published over 40 research articles, some in world-renowned journals such as Physical Review A, Physica A, American Journal of Psychiatry, Schizophrenia Bulletin, and Journal of Neuroscience.

Areas of Research / Professional Expertise

    Neuroscience, Quantum Physics, Quantum Information, Philosophy of Mind, Consciousness

Websites

Books

Featured Title
 Featured Title - Quantum Information and Consciousness - 1st Edition book cover

Articles

Physica E: Low-dimensional Systems and Nanostructures 2020; 124: 114332

Launching of Davydov solitons in protein α-helix spines


Published: Jul 01, 2020 by Physica E: Low-dimensional Systems and Nanostructures 2020; 124: 114332
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Life Science, Mathematics, Nanoscience & Technology, Physics

We describe a general mechanism that launches moving Davydov solitons in the interior of protein α-helices through phase-modulated Gaussian pulses of amide I energy. We also compare the predicted soliton velocity based on effective soliton mass and the observed soliton velocity in computer simulations for different parameter values of the isotropy of the exciton-phonon interaction. The presented results demonstrate the capacity for explicit control of soliton velocity in protein α-helices.

Advances in Quantum Chemistry 2020; vol. 82

Quantum transport and utilization of free energy in protein α-helices


Published: May 02, 2020 by Advances in Quantum Chemistry 2020; vol. 82
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Life Science, Mathematics, Medicine, Physics

The essential biological processes that sustain life are catalyzed by protein nano-engines, which maintain living systems in far-from-equilibrium ordered states. To investigate energetic processes in proteins, we have analyzed the system of generalized Davydov equations that govern the quantum dynamics of multiple amide I exciton quanta propagating along the hydrogen-bonded peptide groups in α-helices.

International Journal of Quantum Information 2020; 18(1): 1941024

Analysis of single-particle nonlocality through the prism of weak measurements


Published: Feb 01, 2020 by International Journal of Quantum Information 2020; 18(1): 1941024
Authors: Danko Georgiev, Eliahu Cohen
Subjects: Mathematics, Physics

We study the nonlocality of single quanta in a square nested Mach–Zehnder interferometer with spatially separated detectors using a delayed choice modification of quantum measurement outcomes that depend on the complex-valued weak values. We show that if spacelike separated Bob and Alice are allowed to freely control their quantum devices, the geometry of the setup constrains the local hidden variable models.

BioSystems 2020; 187: 104051

Inner privacy of conscious experiences and quantum information


Published: Jan 01, 2020 by BioSystems 2020; 187: 104051
Authors: Danko D. Georgiev
Subjects: Life Science, Mathematics, Medicine, Physics

Identifying consciousness with the unobservable quantum information contained by quantum physical brain states allows for application of quantum information theorems to resolve possible paradoxes created by the inner privacy of conscious experiences, and explains how the observable brain is constructed by accessible bits of classical information that are bound by Holevo's theorem and extracted from the physically existing quantum brain upon measurement with physical devices.

Chaos, Solitons and Fractals 2019; 123: 275-293

Quantum tunneling of Davydov solitons through massive barriers


Published: Apr 30, 2019 by Chaos, Solitons and Fractals 2019; 123: 275-293
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Chemistry, Life Science, Mathematics, Physics

We studied computationally whether the Davydov solitons are able to reflect from massive barriers that model the presence of external protein clamps acting on a portion of the α-helix, and characterized the range of barrier conditions for which the Davydov solitons are capable of tunneling through the barrier. The simulations showed that Davydov solitons could reflect from a massive barrier multiple times before successful tunneling through the barrier.

Physica A: Statistical Mechanics and its Applications 2019; 517:257-269

On the quantum dynamics of Davydov solitons in protein α-helices


Published: Nov 30, 2018 by Physica A: Statistical Mechanics and its Applications 2019; 517:257-269
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Chemistry, Life Science, Mathematics, Physics

We studied the transport of energy inside protein α-helices by deriving a system of quantum equations of motion from the Davydov Hamiltonian with the use of the Schrödinger equation and the generalized Ehrenfest theorem. Numerically solving the system of quantum equations of motion for different initial Gaussian distributions of the amide I energy over the peptide groups confirmed the generation of both moving or stationary Davydov solitons.

Physical Review A 2018; 97 (5): 052102

Probing finite coarse-grained virtual Feynman histories with sequential weak values


Published: May 03, 2018 by Physical Review A 2018; 97 (5): 052102
Authors: Danko Georgiev, Eliahu Cohen
Subjects: Mathematics, Physics

We show that sequential weak values, inferred by consecutive weak measurements of projectors, allow direct experimental probing of individual virtual Feynman histories, thereby revealing the exact nature of quantum interference of coherently superposed histories. We also elucidate the relationship between sequential weak values of quantum histories with different coarse graining in time and establish the incompatibility of weak values for nonorthogonal quantum histories in history Hilbert space.

Knowledge-Based Systems 2018; 151: 1-15

Enhancing user creativity: semantic measures for idea generation


Published: Mar 10, 2018 by Knowledge-Based Systems 2018; 151: 1-15
Authors:
Subjects: Biomedical Science, Computer Science & Engineering, Engineering - General, Life Science

Human creativity grants us the power to transform the surrounding world and extend our human attributes beyond what is currently possible. The origin of creativity, however, is poorly understood. Here we analyze a dataset of design problem-solving conversations in real-world settings by using 49 semantic measures based on WordNet 3.1 and demonstrate that a divergence of semantic similarity, an increased information content and a decreased polysemy predict the success of generated ideas.

Progress in Biophysics and Molecular Biology 2018; 135: 16-29

The quantum physics of synaptic communication via the SNARE protein complex


Published: Jan 31, 2018 by Progress in Biophysics and Molecular Biology 2018; 135: 16-29
Authors: Danko D. Georgiev, James F. Glazebrook
Subjects: Life Science, Mathematics, Medicine, Physics

We provide a molecular upgrade of the Beck and Eccles quantum mechanical model of neurotransmitter release by identifying Davydov solitons as quantum quasiparticles that twist the protein α-helices and trigger exocytosis of synaptic vesicles through helical zipping of the SNARE protein complex. We also calculate the observable probabilities for exocytosis based on the mass of Davydov soliton, along with the characteristics of the potential energy barrier through which tunneling is necessary.

International Journal of Modern Physics B 2015; 29 (7): 1550039

Monte Carlo simulation of quantum Zeno effect in the brain


Published: Mar 20, 2015 by International Journal of Modern Physics B 2015; 29 (7): 1550039
Authors: Danko D. Georgiev
Subjects: Life Science, Mathematics, Medicine, Physics

To test whether the mind utilizes quantum Zeno effect to influence brain dynamics, we modeled the brain using quantum tunneling of an electron in a multiple-well structure such as the voltage sensor in neuronal ion channels and performed Monte Carlo simulations of quantum Zeno effect exerted by the mind upon the brain in the presence or absence of environmental decoherence. The simulations showed that the quantum Zeno effect breaks down for timescales greater than the brain decoherence time.

Axiomathes 2013; 23 (4): 683-695

Quantum no-go theorems and consciousness


Published: Jan 12, 2013 by Axiomathes 2013; 23 (4): 683-695
Authors:
Subjects: Life Science, Mathematics, Medicine, Physics

Our conscious minds exist in the universe, therefore they should be identified with physical states that are subject to physical laws. Here, we show that identification of mind states with quantum states within the brain is biologically feasible, and then elaborating on the mathematical proofs of two quantum mechanical no-go theorems, we explain why quantum theory might have profound implications for the scientific understanding of one's mental states, self identity, beliefs and free will.