Shivendu  Ranjan Author of Evaluating Organization Development
FEATURED AUTHOR

Shivendu Ranjan

Senior Research Associate
University of Johannesburg, South Africa

Senior RA @ UJ, South Africa | Head, R&D Ennoble IP| Micro/Nano Scientist | Scientific Author | Book Editor | Book Author | Awardee | Science Freak |

Biography

Dr. Shivendu Ranjan has completed his B.Tech and PhD in Biotechnology from VIT University, Vellore, India and has expertise in Nano(Bio)Technology. He was elected as a Fellow (FLS) of the oldest active biological society started in 1778, The Linnean Society (London) and elected Fellow of Bose Scientific Society (FBSS). In 2018 he has been Elected as Fellow of Indian Chemical Society (FICS) - A society founded in 1924. He has also been elected as Fellow (FIETA) of Indian Engineering Teachers Association. Currently, he is designated as Strategic Head - Research & Development to Ennoble IP Consultancy Pvt. Litd., Noida, India. He is also serving as a Senior Research Associate at Faculty of Engineering & Built Environment, University of Johannesburg, Johannesburg, South Africa. He is also working as Visiting Faculty at National Institute of Pharmaceutical Education and Research-R (NIPER-R), Lucknow, Ministry of Chemicals and Fertilizers, Govt of India. Earlier, he has worked as Scientist at DST-Centre for Policy Research, Lucknow, supported by Ministry of Science and Technology, Govt of India. He also worked as Head, Research & Technology Development at E-Spin Nanotech Pvt. Ltd., SIDBI Incubation Center, Indian Institute of Technology, Kanpur, India. After joining E-Spin Nanotech, IIT Kanpur, he has successfully developed prototypes for many products and have applied 1 patent and has taken lead in the DSIR Certification for R&D Unit of E-Spin Nanotech Pvt Ltd.  He is also Advisor of many companies e.g. Eckovation Solutions Pvt Ltd. (IIT Delhi based start-up), Chaperon Biotech Pvt Ltd (IIT Kanpur based start up), Kyntox Biotech India Pvt Ltd., and Xcellogen Biotech Pvt Ltd. Dr. Shivendu is also reviewer of Iran National Science Foundation (INSF), Tehran, Iran and Jury at Venture Cup, Denmark from past 3 consecutive years. He had founded and drafted the concept for the first edition of the “VIT Bio Summit” in 2012, and the same has been continued till date by the university.
His research interests are multidisciplinary and includes: Micro/Nanobiotechnology applied in pharmaceuticals, nutraceuticals, and environment. He is the Associate Editor of Environmental Chemistry Letters – a Springer journal of 4.6 impact factor – and an editorial board member in Biotechnology and Biotechnological Equipment (Taylor and Francis, USA). He is serving as the Executive Editor of a journal in iMed Press, USA, and also serving as editorial board member and referee for reputed international peer-reviewed journals. He has published seventeen edited books and one authored book in Springer, Switzerland and two with CRC Press, USA. He has recently finished his contract of three volumes of book in Elsevier, two volumes in CRC Press and one with Wiley and RSC (UK) respectively. He has published many scientific articles in international journal of repute with cumulative impact factor of 111.287; Average Impact Factor of 3.589; and h-index of 21. He has bagged several awards and recognition from different national as well as international organizations.

Areas of Research / Professional Expertise

    Shivendu's Research Interests are (but not limited to):

    - Food Micro/Nanotechnology
    - Micro/Nano-Nutraceuticals and Bioavailability
    - Micro/Nano-Therapeutics and Micro/Nanobiotechnology
    - Agricultural Micro/Nanotechnology
    - Micro/Nanomedicine and Nanopharmaceutics
    - Micro/Nanotechnology in Drug and Nutraceutical Delivery
    - Micro/Nanotoxicology and Risk Assessment
    - Polymer Micro/Nanotechnology
    - Micro/Nanotechnology for Clean Water

Personal Interests

    Editorship | Gardening | Cycling | Tech Talk

Websites

Books

Featured Title
 Featured Title - Nanotoxicology: Toxicity Evaluation, Risk Assessment & Mgmt - 1st Edition book cover

Articles

International Journal of Nanomedicine

Titanium dioxide nanoparticle-protein interaction explained by docking approach


Published: Mar 15, 2018 by International Journal of Nanomedicine
Authors: Shivendu Ranjan, Nandita Dasgupta, Sudandiradoss Chinnappan, Chidambaram Ramalingam, Ashutosh Kumar
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

Titanium dioxide has been proven for toxicity by in vitro and in vivo approaches, however, further studies are needed in nano-toxicological research using in silico analysis. In this study, Autodock 4.0.5 was used in an attempt to evaluate the interaction of titanium dioxide with proteins.

Nanotechnology for Environmental Engineering

Graphene oxide MgFe2O4 nanocomposites for Cr(VI) remediation: a comparative modeling study


Published: Jan 12, 2018 by Nanotechnology for Environmental Engineering
Authors: Hosseini S, Talebipour S, Neyestani MR, Ranjan S, Dasgupta N
Subjects: Agricultural Science, Engineering - Environmental, Environmental Science, Nanoscience & Technology

The article describes the synthesis and application of magnesium ferrite nanoparticles (MgFe2O4 NPs) and engineered MgFe2O4 nanocomposites (NCs) by graphene oxide as green and easy separable magnetic adsorbents in removal of Cr(VI) from environmental pollutant.

Colloids and Surfaces B: Biointerfaces

Formulation of vitamin D encapsulated cinnamon oil nanoemulsion: Its potential anti-cancerous activity in human alveolar carcinoma cells


Published: Jan 06, 2018 by Colloids and Surfaces B: Biointerfaces
Authors: Meghani Nikita, Patel Pal, Kansara Krupa, Ranjan Shivendu, Dasgupta Nandita, Chidambaram Ramalingam, Kumar Ashutosh
Subjects: Food & Culinary Science, Life Science, Nanoscience & Technology

Cinnamon Nanoemulsion has been fabricated by ultrasonication approach and further has been analyzed for its cytotoxic analysis.

Environmental Chemistry Letters

Applications of Nanotechnology in agriculture and water quality management


Published: Jun 14, 2017 by Environmental Chemistry Letters
Authors: Nandita Dasgupta, Shivendu Ranjan, Chidambaram Ramalingam
Subjects: Agricultural Science, Life Science, Nanoscience & Technology

Here we review the application of nanotechnology in agriculture and Nanomaterials for agriculture and water quality management.

Biotechnology & Biotechnological Equipment

Nanotechnology towards prevention of anemia and osteoporosis: from concept to market


Published: Jun 08, 2017 by Biotechnology & Biotechnological Equipment
Authors: Shukla A, Dasgupta N, Ranjan S*, Singh S, Chidambaram R
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

This review article highlights the research trends and challenges of nanotechnology based drugs to combat iron deficiency anaemia and osteoporosis. This review outlines the recent research trends in nano-drugs and touches on issues concerning the market, industries and patents pertaining to drugs for anaemia and osteoporosis. To provide the safety and risk factors of nanomaterials, we have briefly highlighted the toxicological aspects of nanomaterials used in drugs.

Critical Reviews in Food Science and Nutrition

Nanomaterials in food and Agriculture: an overview on their safety concerns and regulatory issues


Published: Jun 01, 2017 by Critical Reviews in Food Science and Nutrition
Authors: Aditi Jain, Shivendu Ranjan, Nandita Dasgupta, Chidambaram Ramalingam
Subjects: Agricultural Science, Engineering - Environmental, Environmental Science, Food & Culinary Science, Nanoscience & Technology

This review provides a better understanding of the current scenario of the nanotoxicology, disease progression due to nanomaterials, and their use in the food industry and medical therapeutics. Briefly, the required rules, regulations, and the need of policy-makers has been discussed critically.

Ultrasonics Sonochemistry

Fish Oil Based Vitamin D Nanoencapsulation by Ultrasonication and Bioaccessibility Analysis in Simulated Gastro Intestinal Tract


Published: Jan 11, 2017 by Ultrasonics Sonochemistry
Authors: Walia N, Dasgupta N, Ranjan S, Lingyun C, Chidambaram R
Subjects: Biomedical Science, Food & Culinary Science, Life Science, Nanoscience & Technology

Till date, no one have fabricated an efficient nano-vehicle for the delivery of vitamin D as well as analyzed the efficient delivery system in simulated GI-tract, this is first of its kind study in this regard. This can be scaled up further after analyzing the safety aspects.

Journal of Photochemistry & Photobiology, B: Biology

Nano-zirconia – Evaluation of its antioxidant and anticancer activity


Published: Jan 05, 2017 by Journal of Photochemistry & Photobiology, B: Biology
Authors: Balaji S, Mandal BK, Ranjan S, Dasgupta N, Ramalingam C
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

his is the first study in which E. globulus leaf extract was used to synthesize smaller spherical shaped ZrO2 NPs for improved bioactivity i.e. antioxidant and cytotoxicity.

Journal of Photochemistry & Photobiology, B: Biology

Diastase induced green synthesis of bilayered reduced graphene oxide and its decoration with gold nanoparticles


Published: Jan 01, 2017 by Journal of Photochemistry & Photobiology, B: Biology
Authors: Maddinedi SB, Mandal BK, Patil SH, Andhalkar VV, Ranjan S, Dasgupta N
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

The results have shown that this synthetic method is effective for the production of large-scale graphene in a low cost, simple and green method. Since this process avoids the use of hazardous and toxic substances, the produced DRG/Au composites are likely to offer various potential applications in biology and medicine.

Journal of Photochemistry & Photobiology, B: Biology

Cytotoxicity study of Piper nigrum seed mediated synthesized SnO 2 nanoparticles towards colorectal (HCT116) and lung cancer (A549) cell lines


Published: Jan 01, 2017 by Journal of Photochemistry & Photobiology, B: Biology
Authors: Sai KT, Mandal BK, Ranjan S, Dasgupta N
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

The generated ROS were responsible for the cytotoxicity of SnO2 NPs to the studied cancer cells and smaller size NPs generated more ROS and hence showed higher cytotoxicity over larger size NPs. The results of this study suggest that the synthesized stable nanoparticles could be a potent therapeutic agent towards cancerous cell lines.

Journal of Photochemistry & Photobiology, B: Biology

A spectroscopic study on interaction between bovine serum albumin and titanium dioxide nanoparticle synthesized from microwave-assisted hybrid chemical approach


Published: Nov 06, 2016 by Journal of Photochemistry & Photobiology, B: Biology
Authors: Ranjan S, S, Dasgupta N, Srivastava P, Chidambaram R
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

Highlights 1. TiO2 NP-BSA interaction with major conformational changes of the protein 2. Fluorescence quenching analysis confirms the stable interaction. 3.The pseudo-second order kinetics with equilibrium contact-time of 20 min

Chemico Biological interaction

Bovine serum albumin interacts with silver nanoparticles with a “side-on” or “end on” conformation


Published: Jun 25, 2016 by Chemico Biological interaction
Authors: Ranjan S, Dasgupta N, Patra D, Srivastava P, Kumar A, Ramalingam C
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

The data of the present study determines the detailed evaluation of BSA adsorption on AgNP along with mechanism, kinetics and isotherm of the adsorption.

Environmental Science and Pollution Research

Microwave-irradiation-assisted hybrid chemical approach for titanium dioxide nanoparticle synthesis: microbial and cytotoxicological evaluation


Published: Jun 23, 2016 by Environmental Science and Pollution Research
Authors: Ranjan S, Dasgupta N, Bhavapriya R, Ganesh SA, Chidambaram R, Ashutosh K
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

Therefore, the study determines that the microwave-assisted hybrid chemical approach is time-saving; hence, this technique can be upgraded from lab scale to industrial scale via pilot plant scale. Moreover, it is necessary to find the mechanism of action at the molecular level to establish the reason for greater bacterial and cytotoxicological toxicity. Graphical abstract A graphical representation of TNP synthesis.

Journal of Food Process Engineering

Microwave Blanching: An Emerging Trend in Food Engineering and its Effects on Capsicum annuum L


Published: May 13, 2016 by Journal of Food Process Engineering
Authors: Ranjan S, Dasgupta N, Walia N, Thara CC, Chidambaram R
Subjects: Agricultural Science, Food & Culinary Science

This study shows that microwave blanching of food products is far better approach than other blanching methods as it causes minimal/lesser damage unlike IR blanching and wet blanching methods. This can be said based on the fact that microwave blanching does not involve water as required in the process of wet blanching and, thus, reduces the chances of microbial contamination.

Environmental Science and Pollution Research

Thermal co-reduction approach to vary size of silver nanoparticle: its microbial and cellular toxicology


Published: Mar 01, 2016 by Environmental Science and Pollution Research
Authors: Dasgupta N, Ranjan S, Bhavapriya R, Venkatraman M, Chidambaram R, Avadhani GS, Ashutosh K
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

It has been concluded by this study that the size of AgNPs can be varied, by varying the concentration of reactants and temperature called as "thermal co-reduction" approach, which is one of the suitable approaches to meet the same. Also, the smaller AgNP has shown more microbial and cellular toxicity.

Environmental Chemistry Letters

Titanium dioxide nanoparticles induce bacterial membrane rupture by reactive oxygen species generation


Published: Jan 12, 2016 by Environmental Chemistry Letters
Authors: Ranjan S, Chidambaram R
Subjects: Engineering - Environmental, Environmental Science, Life Science, Nanoscience & Technology

The bacterial inner wall was ruptured, and cytoplasmic content was released after 5 min of treatment in a dose-dependent manner. Notably, superoxide formation was not observed, which establishes the fact that reactive oxygen generation and alteration of membrane integrity, as well as permeability, is the major mechanism of antimicrobial activity of nano-TiO2.

RSC Advances

Assessment on Antibacterial Activity of Nanosized Silica derived from Hypercoordinated Silicon(IV) Precursors


Published: Jan 10, 2016 by RSC Advances
Authors: Janardan S, Suman P, Ragul G, Anjaneyulu U, Ranjan S, Dasgupta N, Ramalingam C, Sasikumar S, Vijayakrishna K, Sivara
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

his work also demonstrates the influence of nano-sized silica particles on antibacterial activity (DIZ, MIC and MBC) i.e. better activity was shown for nano-rods derived from the hypercoordinated silicon complexes than the conventional TEOS (sol–gel) method. Experiments on the generation of reactive oxygen species (ROS) through oxidative stress demonstrate the toxicity of nanosilica particles.

International Journal of Food Properties

Fabrication of Food grade Vitamin E nanoemulsion by low energy approach: characterization and its application


Published: Jun 17, 2015 by International Journal of Food Properties
Authors: Dasgupta N, Ranjan S, Mundra S, Kumar A, Chidambaram R
Subjects: Biomedical Science, Food & Culinary Science, Life Science, Nanoscience & Technology

Further, the high-performance liquid chromatography method was used to determine the vitamin E acetate concentration and encapsulation efficiency for the stable nanoemulsion. These nanoemulsions showed improved bioactivity, antioxidant, and antimicrobial activity and could be potentially used to increase the shelf life of fruit juice.

RSC Advances

Diastase assisted green synthesis of size-controllable gold nanoparticles


Published: Mar 04, 2015 by RSC Advances
Authors: Maddinedi SB, Badal KM, Ranjan S, Dasgupta N
Subjects: Biomedical Science, Life Science, Nanoscience & Technology

In vitro cytotoxicity studies by MTT assay on HCT116 and A549 cancer cells showed that the cytotoxicity of the as-synthesized Au nanocolloids depends on their size and dose.

Food Research International

Nanotechnology in agro-food: from the field to plate


Published: Jan 23, 2015 by Food Research International
Authors: Ranjan S, Dasgupta N, Deepa M, Chidambaram R, Ashutosh K, Rishi S
Subjects: Food & Culinary Science, Life Science, Nanoscience & Technology

This review provides a detailed overview of the application of nanotechnology in the field of agriculture, and food science & technology. Additionally, a brief idea about the classification of nanomaterials, synthesis and characterization techniques is discussed.

Journal of Nanoparticle Research

Nanoscience and nanotechnologies in food industries: opportunities and research trends


Published: May 29, 2014 by Journal of Nanoparticle Research
Authors: Ranjan S, Dasgupta N, Arkadyuti RC, Melvin SS, Chidambaram R, Rishi S, Ashutosh K
Subjects: Food & Culinary Science, Life Science, Nanoscience & Technology

This review is focused on application of nanotechnology in food industries. It also gives insight on commercial products in market with usage of nanomaterials, current research and future aspects in these areas.

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