BiographySandeep Kumar is a Senior Principal scientist in Biotherapeutics Pharmaceutical Research & Development at the Saint Louis laboratories of Pfizer, Inc. He is involved in computational modeling and developability risk assessments of biotherapeutic drug candidates including monoclonal antibodies, fusion proteins and antibody-drug conjugates. He is trying to understand molecular basis of protein aggregation, immunogenicity, viscosity and other challenges encountered during biotherapeutic drug development. Sandeep Kumar has been advocating de-risking biopharmaceutical drug development by including considerations of develop-ability and safety, along with potency, during design / selection of biotherapeutic candidates. Sandeep has contributed towards more than 60 research papers, review articles and book chapters, and delivered more than 30 invited talks. He has also co-edited a book entitled “Developability of Biotherapeutics: Computational Approaches” along with Dr. Satish Singh of Pfizer Inc.
Sandeep Kumar holds a Bachelor’s degree in Physics from Delhi University, a Master’s degree in Biotechnology and Molecular Biology from G. B. Pant University of Agriculture and Technology, and a Doctorate in Computational molecular biophysics from Indian Institute of Science, Bangalore. This was followed by postdoctoral research under Prof. Ruth Nussinov guidance at NCI-Frederick, NIH, on protein folding, function and thermodynamic stability. Sandeep has received several awards including W. E. Upjohn Prize from Pfizer, Inc., Ebert Prize from American Pharmacists Association, Fogarty postdoctoral fellowship from NIH, and junior and senior research fellowships from CSIR, India.
Areas of Research / Professional Expertise
Molecular Biophysics, Computational Chemistry, Protein Structure--function