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This chapter reviews what is known about nucleotides, immunity, and infection, and draws from studies in both experimental animal models and in human infants. Dietary nucleotides have a limited capacity for absorption in the intestinal tract, possibly as a result of the lack of a nucleotide transport system and the presence of negatively charged phosphate groups, which hinder absorption. The most common nucleotides can be divided into two groups, purines and pyrimidines, based on the structure of the nitrogenous base. The chapter shows the catabolic pathways for purine nucleotides and pyrimidine nucleotides in humans.

From: Nutrition, Immunity, and Infection

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