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This sample chapters are from the following books:

Cluster Randomised Trials, Second Edition
 
Richard J. Hayes
Lawrence H. Moulton

Cluster Randomised Trials, Second Edition explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, it covers basic concepts underlying the use of cluster randomisation.



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Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials
 
John O'Quigley, University of Pierre and Marie Curie, Paris, France
Alexia Iasonos, Memorial Sloan Kettering Cancer Center, New York, USA
Björn Bornkamp, Novartis Pharma AG, Basel, Switzerland

This handbook will provide an overview of most up-to-date statistical methods required for design, monitoring and analysis for dose finding clinical trials, focusing both on the clinical aspects as well as statistical considerations. This handbook will not cover statistical methods for Phase II non-dose finding studies or Phase III clinical trials.



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Absolute Risk: Methods and Applications in Clinical Management and Public Health
 
Ruth M. Pfeiffer, National Cancer Institute, Rockville, Maryland, USA
Mitchell H. Gail, National Cancer Institute, Rockville, Maryland, USA

This book addresses the development, evaluation, and application of models of absolute risk- the probability of developing a specific disease over a specified time interval in the presence of competing causes of mortality. It discusses the development of appropriate statistical methods for estimating and applying absolute risk.



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