560 Pages 200 B/W Illustrations
    by CRC Press

    Focusing on the scientific basis of skin moisturization, this expanded Second Edition of Skin Moisturization explores a wide range of topics, from the biological aspects of the skin to the formulation of the active ingredients in skin moisturizers. Ideal for dermatologists, cosmetic scientists, and clinical scientists interested in the treatment of xerotic skin conditions, the text discusses the latest technology and trends in the ever-growing and expanding cosmetic industry.

    1. Epidermal differentiation. 2. Lipid organization of the skin barrier.  3. Untangling the role of keratin in Stratum corneum.  4. Filaggrin. 5. Peptidylarginine deiminases in skin biology.  6. Cornified envelope.  7. Corneodesmosomal proteins.   8. Kallikrein-related peptidases.   9. Aquaporins and Tight junctions.  10. Epidermal pH  11. The molecular aspects of dry flaky skin conditions. 12. Xerotic Skin Conditions and SC Properties.  13. Skin barrier dysfunction in atopic dermatitis.   14. Self -perceived sensitive skin.  15. Psychological stress and dry skin. 16.  Stratum corneum biomechanics. 17. Glycerol as humectant.  18. Lanolin and the skin. 19. Moisturization mechanisms.  20. The effects of niacinamide-containing moisturizers.   21. Urea as a moisturizing and barrier-enhancing ingredient.   22. Hydroxyacids and salicylic acid.   23. Stratum corneum serine proteases and effect of inhibitors on dry skin.  24.  Cannabinoids and pruritus  25.  Microdermabrasion.   26. Cosmetic benefits derived from the topical application of acid proteases.   27. Skin moisturization by dermonutrition.   28. Capacitance imaging for viewing and measuring skin surface hydration.   29. Vibrational imaging and microspectroscopy.  30. Measuring water gradients using Confocal Raman Miscrospectroscopy.  31. New developments in skin barrier measurements.

    Biography

    Anthony V. Rawlings, James J. Leyden

    "Researchers, geneticists and academicians specializing in the study of skin barrier function and keratinazation disorders will be delighted to add this book to their library."

    "The chapters devoted to Atopic Dermatitis contains some of the best explanations for the pathogenesis of eczema that I have encountered."

    "I would highly recommend it to any dermatologist interested in critically evaluating and designing the perfect moisturizer".

    -Patricia Wong, MD (Stanford University Medical Center)