1st Edition

New Perspectives in Monitoring Lung Inflammation Analysis of Exhaled Breath Condensate

Edited By Paolo Montuschi Copyright 2013
    232 Pages 27 B/W Illustrations
    by CRC Press

    Attracting the attention of the medical community, exhaled breath condensate is a completely non-invasive method for sampling secretions from the airways. Analysis of exhaled breath condensate is potentially useful for monitoring airway inflammation and in pharmacological therapy. With its non-invasive nature, this method may be suitable for longitudinal studies even in children and in patients with lung severe disease.

    New Perspectives in Monitoring Lung Inflammation provides an introduction to the analysis of exhaled breath condensate for monitoring lung inflammation. The book presents current knowledge on the physicochemical properties of exhaled breath condensate and its formation in the airways and covers important aspects of the methodology. It details markers, and classes of markers, of airway inflammation in separate chapters and discusses the use of the technique in adults and children. The text also reviews the implications for drug development and future research. The volume concludes with an overview of lung inflammation focusing on basic and clinical pharmacology of important mediators.

    Presenting a comprehensive view of exhaled breath condensate, the text explains how this method could play a major role in the diagnosis and therapy of lung diseases, and may launch a new era in respiratory medicine.

    Exhaled Breath Condensate: A New Approach to Monitoring Lung Inflammation, Peter J. Barnes
    Analysis of Exhaled Breath Condensate: Methodological Issues, Paolo Montuschi
    Exhaled Breath Condensate: Formation and Physicochemical Properties, Richard M. Effros
    Isoprostanes, Prostanoids, and Leukotrienes in Exhaled Breath Condensate, Paolo Montuschi
    Hydrogen Peroxide in Exhaled Breath Condensate, Wendy J.C. van Beurden and Richard Dekhuijzen
    Measurement of Exhaled Breath Condensate pH: Implications for Pathophysiology and Monitoring of Inflammatory Airway Diseases, Benjamin Gaston and John F Hunt
    Nitric Oxide-Derived Products in Exhaled Breath Condensate, Sergei A. Kharitonov
    Analysis of Exhaled Breath Condensate in Children, Rijn Jobsis and Philippe P.R. Rosias
    Exhaled Breath Condensate: Comparisons with Other Methods for Assessing Lund Inflammation, Philip Silkoff and Christopher A. Bates
    Analysis of Exhaled Breath Condensate: Potential Implications for Diagnosis and Therapy of Lung Diseases, Umur Hatipoglu and Israel Rubinstein
    Analysis of Exhaled Breath Condensate: Directions for Future Research, Jon L. Freels and Richard A. Robbins
    The Role of Leukotrienes and Prostonoids in Airway Inflammation, James R. Sheller, R. Stokes Peebles, and Ryszard Dworski
    Neurogenic Inflammation in the Airways, Guy Joos, Katelijne O. de Swert, and Romain A. Pauwels
    The Role of Cytokines and Chemokines in Airway Inflammation, Louise Donnelly and Suzanne Traves

    Biography

    Paolo Montuschi

    "…an excellent introduction of the analysis of exhaled breath condensate."
    -Doody's Reviews