4th Edition
NMR and Chemistry An introduction to modern NMR spectroscopy, Fourth Edition
Keeping mathematics to a minimum, this book introduces nuclear properties, nuclear screening, chemical shift, spin-spin coupling, and relaxation. It is one of the few books that provides the student with the physical background to NMR spectroscopy from the point of view of the whole of the periodic table rather than concentrating on the narrow applications of 1H and 13C NMR spectroscopy. Aids to structure determination, such as decoupling, the nuclear Overhauser effect, INEPT, DEPT, and special editing, and two dimensional NMR spectroscopy are discussed in detail with examples, including the complete assignment of the 1H and 13C NMR spectra of D-amygdain.
The authors examine the requirements of a modern spectrometer and the effects of pulses and discuss the effects of dynamic processes as a function of temperature or pressure on NMR spectra. The book concludes with chapters on some of the applications of NMR spectroscopy to medical and non-medical imaging techniques and solid state chemistry of both I = F1/2 and I > F1/2 nuclei. Examples and problems, mainly from the recent inorganic/organometallic chemistry literature support the text throughout. Brief answers to all the problems are provided in the text with full answers at the end of the book.
The Properties of the Nucleus of an Atom
The Nucleus in a Magnetic Field
The Source of the NMR Signal
A Basic NMR Spetrometer
Questions
THE MAGNETIC FIELD AT THE NUCLEUS: NUCLEAR SCREENING THE CHEMICAL SHIFT
Effects Due to the Molecule
Isotope Effects
Effects Due to Unpaired Electrons
The Chemical Shift
Note on Sample Preparation, Standardization, and Solvent and Temperature Effects
Questions
INTERNUCLEAR SPIN-SPIN COUPLING
The Mutual Effects of Nuclear Magnets on Resonance Positions
The Appearance of Multiplets Arising form Spin-Spin Coupling
Spin-Spin Coupling Satellites
The Description of Spin Systems
Second-Order Effects
Questions
NUCLEAR MAGNETIC RELAXATION
Relaxation Processes in Assemblies of Nuclear Spins
Dipole-Dipole Relaxation
Quardrupolar Relaxation
Spin Rotation Relaxation: Detailed Molecular Motion
Chemical Shift Anisotropy Relaxation
Scalar Relaxation
Examples of 13C Relaxation Times
Questions
THE SPECTROMETER
The Magnet and Field Homogeneity
The Probe
Field-Frequency Lock
The Transmitter
The Detection System
Production of the Spectrum
Rapid Multiple Pulsing
Manipulations of Collected Data
Questions
MAKING THE SPINS DANCE
Decoupling
Composite Pulses
Refocusing Pulse
Questions
NMR SPECTRA OF EXCHANGING AND REACTING SYSTEMS
Systems at Equilibrium
Reaction Monitoring of Systems not at Equilibrium
Questions
MULTIPLE RESONANCE AND ONE-DIMENSIONAL PULSE SEQUENCES
Decoupling Difference Spectroscopy
The Nuclear Overhauser Effect
One-Dimensional Mutliphase Sequences
Exercises in Spectral Interpretation
TWO-DIMENSIONAL NMR SPECTROSCOPY
J-Resolved Two-Dimensional NMR Spectroscopy
Homonuclear COSY NMR Spectroscopy
Heteronuclear COSY NMR Spectroscopy
HOHAHA or TOCSY
Two-Dimensional INADEQUATE
Overhauser and Magnetization Transfer Based Two-Dimensional NMR Spectroscopy
Inverse Detection
Three-Dimensional NMR Spectroscopy
Questions
MAGNETIC RESONANCE IMAGING AND BIOMEDICAL NMR
Producing an Image
Whole Body Imaging
Diffusion and Flow
Chemical Shift Imaging
Biological Uses of Imaging - Imaging Microscopy
Industrial Uses of Imaging Techniques
Biomedical NMR
HIGH-RESOLUTION SOLID-STATE NMR
Magic Angle Spinning
Spin-1/2 Nuclei with Low Magnetogyric Ratios
I=1/2 Nuclei with High Magnetogyric Ratios
MAS of Quadropolar Nuclei
Some Applications
Deuterium, An Integral-Spin Nucleus
Questions
Bibliography
Answers to Questions
Index
Biography
Akitt, J.W.; Mann, B. E.
