1st Edition

The Microbe-Host Interface in Respiratory Tract Infections

Edited By Jan L. L. Kimpen, Octavio Ramilo Copyright 2005

    The molecular pathogenesis of microbial agents responsible for respiratory tract infections (RTIs) has been the focus of much research in recent years. The emphasis has been on developing new treatments such as novel antimicrobials and more effective vaccines. Significant attention has also been paid to improving molecular diagnostic methods to identify RTI-causing microbes, as well as understanding the host response to them.

    The Microbe-Host Interface in Respiratory Tract Infections presents an overview of the current knowledge in this area. It provides us with the first coherent picture of emerging strategies for controlling the microbes responsible for RTIs. This comprehensive volume is divided into three sections: the first reviews topics of general interest; the second focuses on bacterial and atypical RTIs; while the final section covers viral RTIs. Each of the chapters is the work of two or more of the top scientists in the field writing about their own pioneering research. Various chapters comment on vaccines, antibiotics, and molecular diagnostic methods.

    This cutting-edge work is essential reading for research microbiologists and other scientists involved in the investigation and treatment of RTIs.

    Relevance of Genetic Background in Respiratory Tract Infections, T.G. Kimman and B. Hoebee

    The Hygiene Hypothesis: The Role of Microbes in the Prevention of Atopy and Atopic Disease, L.E.M. Niers, T.J. Steenhuis, and M.O. Hoekstra

    Respiratory Infection in the Immunocompromised Host: Recognition and Treatment, A.R. Gennery and A.J. Cant

    New Diagnostic Modalities In Respiratory Tract Disease, A. Van Belkum and H.G.M. Niesters

    The Pathogenesis of Bacterial Respiratory Tract Infection and Bronchitis, J. Zweigner and E. Tuomanen

    The Role of Atypical Agents in Respiratory Tract Disease, M. Fonseca-Aten, A.M. Rios and R.D. Hardy

    Infections in Patients with Cystic Fibrosis: Effects of a Longer Survival, H.E. Elphick and R.L. Smyth

    Antibiotic Treatment of Lower Respiratory Tract Infection, F. Ghaffar and O. Ramilo

    Vaccines in the Prevention of Bacterial Respiratory Tract Infections in Children, R.H. Veenhoven and E.A.M. Sanders

    Pathogenesis of Respiratory Syncytial Virus Bronchiolitis: Immunological Aspects , J. Heidema, J.L.L. Kimpen, and G.M. van Bleek

    Viral Infections and Childhood Asthma, M.J.J. Ermers and L. Bont

    Adenovirus, L.M. Haveman, M. Bierings and T.F.W. Wolfs

    Rhinovirus: Is It Really a Relevant Pathogen? O. Ruuskanen and T. Hyypiä

    Biography

    Jan L. L. Kimpen, Octavio Ramilo

    "…comprehensive…well-written, valuable…provides a sound, scientific base of knowledge."
    Clinical Infectious Diseases, 2005