198 Pages
by
CRC Press
198 Pages
by
CRC Press
198 Pages
by
Routledge
Also available as eBook on:
This new text provides a practical guide to hydrophilic polymer coatings technology for applications in a wide range of medical materials and devices. It concisely provides both the scientific basics of this class of polymers and the up-to-date information needed for product development and evaluation, processing, manufacturing, and regulatory compliance. More than fifty schematics illustrate materials, processes, and equipment. The entire presentation is oriented to the practical needs of personnel involved in product development and evaluation, process engineering, and manufacturing management.
Each chapter ends with a Citations section. Preface The Property of Wettability
Introduction
Wettability
Factors Affecting Surface Tensions and Contact Angles
Measuring Surface Tensions and Contact Angles
Wettability of Polymer Surfaces
Hydrophilicity and the Structure of Hydrophilic Systems
Introduction
Contribution of Molecular Structure
Hydrogels
Aspects of the Network Structure
Aspects of the Surface Structure
Factors Affecting Swelling Characteristics
Quantifying Useful Properties
Common Hydrophilic Polymers
Introduction
Synthetic Hydrophilic Polymers
Hydrophilic Polymers Prepared from Naturally Occurring Materials
Considerations for Development and Manufacture
Introduction
Overview of Coating Technology
Product-, Process-, and Facility-Related Considerations
Surface Preparation
Cleaning Operations
Plasma Treatment
Other Methods of Surface Treatment
Coating Application and Curing Techniques
Methods of Application
Methods of Curing
Additional Technologies
Surface Analysis, Testing Methods, and Process Monitoring
Surface Analysis
Testing Methods
Regulatory and Safety Concerns
Regulatory Considerations
Safety Considerations
Applications
Lubricious Coatings
Drug Delivery Systems
Implants
Conclusion
Index
54 Figures, 4 Tables
Introduction
Wettability
Factors Affecting Surface Tensions and Contact Angles
Measuring Surface Tensions and Contact Angles
Wettability of Polymer Surfaces
Hydrophilicity and the Structure of Hydrophilic Systems
Introduction
Contribution of Molecular Structure
Hydrogels
Aspects of the Network Structure
Aspects of the Surface Structure
Factors Affecting Swelling Characteristics
Quantifying Useful Properties
Common Hydrophilic Polymers
Introduction
Synthetic Hydrophilic Polymers
Hydrophilic Polymers Prepared from Naturally Occurring Materials
Considerations for Development and Manufacture
Introduction
Overview of Coating Technology
Product-, Process-, and Facility-Related Considerations
Surface Preparation
Cleaning Operations
Plasma Treatment
Other Methods of Surface Treatment
Coating Application and Curing Techniques
Methods of Application
Methods of Curing
Additional Technologies
Surface Analysis, Testing Methods, and Process Monitoring
Surface Analysis
Testing Methods
Regulatory and Safety Concerns
Regulatory Considerations
Safety Considerations
Applications
Lubricious Coatings
Drug Delivery Systems
Implants
Conclusion
Index
54 Figures, 4 Tables
Biography
Richard J. LaPorte