5th Edition

A Manual of Neonatal Intensive Care

By Janet M Rennie, Giles Kendall Copyright 2013
    424 Pages 100 B/W Illustrations
    by CRC Press

    424 Pages
    by CRC Press

    Highly Commended, BMA Medical Book Awards 2014

    The fifth edition of this highly successful and well-regarded book continues to provide those working in neonatal intensive care units with precise instructions on the diagnosis and management of common neonatal problems. This edition has been extensively updated and revised, while retaining the background physiology, key references, and diagrams that made previous editions so successful.

    Several new chapters have been added, including the subjects of fetal medicine, antenatal diagnosis, and obstetrics for the neonatologist. Using a clear, accessible style, this edition features discussions of evidence-based medicine and the introduction of additional easy-to-digest lists. The text has been made more internationally applicable, including a re-focus of the chapter on organization of neonatal care away from UK-specific admission criteria and more towards general reasons for admitting a baby to the intensive care ward.

    A Manual for Neonatal Intensive Care provides invaluable guidance for trainees in pediatrics, neonatology, and neonatal nursing and forms a useful ready-reference for the practicing pediatrician and nurse.

    Epidemiology and neonatal outcomes
    Epidemiology: definitions in perinatal medicine
    Neonatal outcomes
    References
    Further reading
    Web links

    Organization of neonatal care
    Organization of neonatal care: definition of levels of care
    Provision of intensive care facilities
    References

    Clinical governance, risk management and legal aspects of neonatal practice
    Clinical Governance
    Serious untoward incident (SUI) reporting and investigation
    Medical negligence
    Consent
    Death
    Further reading

    Maternal-fetal medicine for the neonatologist
    Prenatal diagnosis of fetal disease
    Maternal conditions affecting the fetus
    Hypertension in pregnancy
    Multiple pregnancy
    Immunological conditions
    Placental insufficiency
    Preterm membrane rupture
    Prelabour rupture of the membranes at term
    Induction of labour
    Intrapartum monitoring
    Mode of delivery
    Further information
    Further reading

    Genetic disease
    Good ‘handles’ for genetic diagnosis
    Further reading
    Web links

    Neonatal resuscitation and stabilization
    Physiological adaptation at birth
    Neonatal resuscitation
    Resuscitation equipment
    Practice of neonatal resuscitation
    Special situations in neonatal resuscitation
    Problems with resuscitation
    First-hour care after resuscitation
    References
    Further reading

    Nursing, monitoring and transport of the sick neonate
    Thermal control
    Minimal handling
    Monitoring
    Clinical and laboratory monitoring
    References

    Physical examination of the newborn
    Timing of the examination
    Physical examination of the newborn
    References
    Further reading

    Congenital anomalies and common postnatal problems
    Common findings in day-to-day practice
    Reference
    Further reading
    Web link

    Fluid and electrolyte balance
    Neonatal renal function and physiology
    Water
    Sodium
    Potassium
    Hydrogen ions and bicarbonate
    Calcium and phosphate
    Magnesium
    Practical fluid and electrolyte management
    References
    Further reading

    Neonatal enteral nutrition
    Infant nutrient requirements
    Which milk to give?
    Anti-infection agents
    Healthy LBW babies
    Sick LBW babies
    References
    Further reading
    Web link

    Parenteral nutrition
    Composition of parenteral nutrition solutions
    Intravenous feeding solutions
    Route of infusion
    Monitoring of i.v. feeding
    Complications of PN
    References
    Further reading

    Acute disorders of the respiratory tract
    Respiratory physiology
    Differential diagnosis of neonatal respiratory disease
    Respiratory distress syndrome (RDS); hyaline membrane disease (HMD)
    Treatment of RDS
    Continuous positive airways pressure (CPAP)
    Mechanical ventilation: intermittent positive pressure ventilation
    Ventilation
    Sudden deterioration on IPPV
    Gradual deterioration on IPPV
    Transient tachypnoea of the newborn
    Meconium aspiration
    Pulmonary interstitial emphysema (PIE), pneumothorax, pneumomediastinum
    Massive pulmonary haemorrhage
    Persistent pulmonary hypertension of the newborn (PPHN)
    Pulmonary hypoplasia
    Congenital malformations affecting the respiratory tract
    References
    Further reading

    Chronic lung disease
    Interventions for chronic lung disease
    Wilson–Mikity syndrome
    References
    Further reading

    Apnoeic attacks
    Definition of apnoea and periodic breathing
    Clinically significant apnoea
    Recurrent apnoea of prematurity
    Pathophysiology
    Radiology
    Treatment
    References
    Further reading

    Infection
    Infection control in neonatal units
    Host defences in the newborn and the inflammatory response
    Bacterial infection in the newborn
    Maintenance of homeostasis
    Virus infections
    Congenital infections
    Effect of perinatal maternal infections
    References
    Further reading

    Neurological problems
    Assessment of the nervous system
    Convulsions in the newborn
    Hypoxic ischaemic encephalopathy (HIE)
    Focal vascular lesions
    Extracranial haemorrhage
    Intracranial haemorrhage
    Preterm white matter injury/periventricular leukomalacia (PVL)
    Neonatal hypotonia
    Nerve palsies
    Central nervous system malformations

    Metabolic disorders, including glucose homeostasis and inborn errors of metabolism
    Glucose metabolism in the newborn
    Clinical causes of hypoglycaemia
    Unusual cases of neonatal hypoglycaemia
    Neonatal hyperglycaemia
    Inborn errors of metabolism
    Causes of severe early metabolic disease
    References
    Further reading

    Endocrine disorders
    Introduction
    Congenital adrenal hyperplasia
    Thyroid problems
    Further reading

    Neonatal jaundice and liver disease
    Physiology
    Bilirubin biochemistry
    Bilirubin encephalopathy (kernicterus)
    Differential diagnosis of neonatal jaundice
    Causes of unconjugated hyperbilirubinaemia
    Breast feeding and jaundice
    Some specific causes of unconjugated hyperbilirubinaemia
    Prolonged neonatal jaundice
    Prolonged unconjugated hyperbilirubinaemia
    Conjugated hyperbilirubinaemia
    Treatment of neonatal jaundice

    Gastroenterological problems
    Basic physiology of the fetal and neonatal gut
    Cleft lip and palate
    Oesophageal atresia and trachea-oesophageal fistula
    Intestinal obstruction
    Exomphalos
    Gastroschisis
    Necrotizing enterocolitis
    Isolated bowel perforation
    Short bowel syndrome
    Gastro-oesophageal reflux
    The baby with persistent vomiting
    Persisting diarrhea
    Haematemesis, melaena and bloody stools in the newborn
    Hirschprung’s disease
    References
    Further reading

    Congenital heart disease in the neonatal period
    The fetal circulation
    Changes in the circulation at birth
    Presentation of heart disease
    Investigations
    Heart murmurs in asymptomatic babies
    CHD presenting as shock with acidosis
    CHD presenting as heart failure
    Treatment of heart failure in the newborn
    Individual conditions which can cause heart failure or shock
    Cyanotic heart disease
    Arrhythmias in the neonatal period
    References
    Arrhythmias in the neonatal period

    Neonatal haematology
    Anaemia in the neonate
    Haemolytic disease of the newborn
    Guidelines for DAT+ babies
    Bleeding and bruising
    Neonatal thrombosis
    References
    Web links

    Genitourinary problems
    Urine
    Renal failure
    Urinary tract infection
    Congenital nephrotic syndrome
    Renal malformations
    Genitourinary tract anomalies
    References
    Further reading

    Eye disorders
    Retinopathy of prematurity
    Buphthalmos (neonatal glaucoma)
    Cataract
    Conjunctivitis
    Strabismus
    References
    Further reading

    Skin disorders
    Common benign neonatal skin disorders
    Other miscellaneous neonatal skin conditions
    Birthmarks and vascular disorders
    Further reading

    Orthopaedic and bone disorders
    Fractures
    Dislocations
    Skeletal malformations
    Further reading

    Neonatal abstinence syndrome
    Maternal opiate abuse
    References
    Further reading

    Procedures and iatrogenic complications
    Neonatal procedures
    Blood sampling and cannulation
    Management of extravasation injury
    Umbilical catherization
    Intraosseous lines
    Endotracheal intubation
    Urine collection
    Reference
    Further reading

    Appendix 1 Growth charts

    Appendix 2 Assessing the ill neonate
    Respiratory severity scoring
    Clinical Risk Index for Babies – CRIB II score
    References

    Appendix 3 Normal blood pressure
    Term neonates
    Preterm infants
    References

    Appendix 4 The neonatal ECG
    Rate and rhythm
    The axis
    Information about the atria
    Information about the ventricles

    Appendix 5 Normal biochemical values in the newborn

    Appendix 6 Haematological values in the newborn
    References

    Appendix 7 Normal CSF values in the newborn
    Traumatic lumbar puncture
    Reference

    Biography

    Janet M Rennie, Consultant and Senior Lecturer in Neonatal Medicine, Elizabeth Garrett Anderson Obstetric Hospital, University College London Hospitals, UKGiles Kendall, Academic Clinical Lecturer in Neonatal Neuroimaging and Neuroprotection, UCL Elizabeth Garrett Anderson Institute for Women's Health and University College London Hospitals, UK

    " … very well covered in a style that is easy to access, with some excellent diagrams illustrating the text well. The layout of the book is very well structured, making quick reference easy. It is the type of book that a practitioner can dip into quickly to access information about a topic and gain a basic concept in a short space of time."
    —Sarah Carey, Deputy Sister, Peterborough City Hospital

    "This is a well-balanced text that is user-friendly on the shop floor and provides a good level of explanatory detail. … . Every neonatal unit and paediatric trainee should have a copy of  this book – it is a definitive text. Highly Commended."
    —2014 BMA Medical Book Awards

    " … a good starting point for nurses new to the neonatal setting as it gives good advice about aspects of care and basic information about most of the scenarios likely to be encountered in an easy to understand language. This is a delightful book to have in the neonatal unit library for all staff to access."
    Practising Midwife