3rd Edition

Introduction to Pharmacology

By Mannfred A. Hollinger Copyright 2007
    460 Pages 80 B/W Illustrations
    by CRC Press

    460 Pages
    by CRC Press

    Advances in pharmacogenomics and proteomics, along with the introduction of recombinant DNA technology, have expanded the applications of pharmacology to encompass a range of disciplines. Biomedical researchers, protein specialists, and molecular biologists are all involved in the development and delivery of novel drugs. Therefore, students in a variety of life sciences now require grounding in pharmacology.

    Adding much new material, Introduction to Pharmacology, Third Edition familiarizes students with the curative action of specific drugs, along with current research and the multifaceted role of pharmacology in society.

    New to the third edition—

    ·      Chapters on smooth muscle pharmacology covering gastrointestinal and pulmonary pharmacology

    ·      Pharmacology advances at the molecular level

    ·      The historical background of the Watson Crick model of DNA

    ·      Cutting edge topics such as RNA interference and dopamine signaling

    The text begins with a discussion on the absorption, distribution, metabolism, and elimination of drugs. Much emphasis is placed on pharmacokinetic aspects: how drugs produce an effect and the quantification of these effects for comparative purposes. Also the text describes substance abuse pharmacology and the evolution of drug laws. Several chapters deal with the development of drugs and challenges faced in drug discovery.

    Identifying both the therapeutic and toxicological aspects of drug use, Introduction to Pharmacology employs contemporary examples to help students become familiar with drug development and treatment, as well as possible adverse affects, and the impact of drug research and use on society today and into the future.

    PART I- FUNDAMENTALS OF PHARMACOKINETICS
    Introduction
    Absorption and Distribution
    Metabolism and Elimination
    Drug Interaction
    PART II- FUNDAMENTALS OF PHARMACODYNAMICS AND TOXICODYNAMICS
    Drug Receptors
    Dose-Response Relationship
    Drug Toxicity
    Treating Drug Toxicity
    PART III- DRUGS THAT REPLACE, CURE, OR TREAT SYMPTOMS
    Hormones
    Chemotherapeutic Agents: Antibiotics and Anticancer Drugs
    Drug Treatment of Symptoms: Neuropharmacology and Substance Abuse
    Cardiovascular Drugs
    Pulmonary Pharmacology
    Gastrointestinal Pharmacology
    PART IV- DRUG DEVELOPMENT
    Drug Discovery by the Pharmaceutical Industry
    Pharmaceutical Development of Drugs and the FDA
    Animals in Research
    Alternative Medicine
    PART V- APPENDICES, GLOSSARY, AND CALCULTIONS
    Appendix I: The History of Drug Abuse Laws in the United States
    Appendix II: Molecular Structure of Nucleic Acids
    Appendix III: Glossary
    Appendix IV: Top 10 Drugs in History
    Appendix V: Answers to Self-Assessment Questions

    Biography

    Mannfred A. Hollinger

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