Clinical Tuberculosis, Fifth Edition

Edited by Peter D O Davies, Stephen B Gordon, Geraint Davies

© 2014 – CRC Press

477 pages | 152 B/W Illus.

Purchasing Options:
Pack - Book and Ebook: 9781444154344
pub: 2014-04-30
US Dollars$239.95

e–Inspection Copy

About the Book

Completely updated and revised, Clinical Tuberculosis continues to provide the TB practitioner—whether in public health, laboratory science or clinical practice—with a synoptic and definitive account of the latest methods of diagnosis, treatment and control of this challenging and debilitating disease.

New in the Fifth Edition:

  • Gamma interferon-based blood tests for the screening of latent infection
  • New molecular techniques for diagnosing the species of Mycobacterium and identifying the gene for rifampicin resistance
  • Updated content on the human immune response to the tubercle bacillus
  • Details of microscopic observation for drug sensitivity
  • Expanded sections on the management and control of TB both locally and globally
  • A wealth of new diagrams and clinical photographs
  • Access to companion eBook included with the print book

Table of Contents


The History of Tuberculosis from Earliest Times to the Development of Drugs; Charlotte A. Roberts and Jane E. Buikstra

Epidemiology; Ted Cohen and Christopher Dye

Pathology and Immunology

Mycobacterium tuberculosis – The Organism; John M. Grange

Genotyping and Its Implications for Transmission Dynamics and Tuberculosis Control; Laura Anderson

Histopathology; Helen C. Wainwright


Immunodiagnosis of Tuberculosis Infection; Ajit Lalvani, Manish Pareek and Katrina Pollock

Diagnosis of Tuberculosis; Luis E. Cuevas

Tuberculosis Clinical Immunology; Robert S. Wallis

Clinical Aspects

Respiratory Tuberculosis; Aravind Ponnuswamy

Tuberculosis of the Central Nervous System; Guy Thwaites

Non-Respiratory Tuberculosis; Peter Ormerod

Tuberculosis in Childhood; Delane Shingadia


Clinical Pharmacology of the Anti-Tuberculosis Drugs; Abdullah AlSultan and Charles A. Peloquin

Chemotherapy Including Drug-Resistant Therapy; Gerry Davies

New Developments in Drug Treatment; Alexander S. Pym

The Surgical Management of Tuberculosis and Its Complications; Richard S. Steyn

Tuberculosis in Special Situations

Human Immunodeficiency Virus and Tuberculosis Co-Infection; Keertan Dheda and Greg Calligaro

Tuberculosis and Migration; Einar Heldal

Tuberculosis and Poverty: A Clinical Perspective; S. Bertel Squire

Multi- and Extreme Drug Resistance: The Experience of India; Zarir F. Udwadia


Preventive Therapy; Jean-Pierre Zellweger

Bacille Calmette–Guerin and Prospects for New Vaccines against Tuberculosis; Helen McShane


Community Approaches to Tuberculosis Treatment; Kwonjune J. Seung and Michael L. Rich

Control of Tuberculosis in Low-incidence Countries; Ibrahim Abubakar and Robert Aldridge

Control of Tuberculosis in High-Prevalence Countries; Jayant N. Banavaliker

The Role of the Tuberculosis Nurse Specialist; Christine E. Bell

Related Aspects

Non-Tuberculous Mycobacteria; Jakko van Ingen

Animal Tuberculosis; Dirk U. Pfeiffer and Leigh A. L. Corner



About the Editors

Peter D O Davies

MA DM FRCP, Professor and Consultant Physician, Liverpool Heart and Chest Hospital, Liverpool, UK

Stephen B Gordon

MA MD FRCP DTM&H, Head of Department, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK

Geraint Davies

BM FRCP PhD DTM&H, Reader in Infection Pharmacology and Consultant in Infectious Diseases, University of Liverpool, UK

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Infectious Diseases
MEDICAL / Public Health
MEDICAL / Pulmonary & Thoracic Medicine