This book summarises the authors’ 20 years of research on the measurement of soft tissue elasticity in vivo. Clinical applications include assessment of tissue fibrosis after radiotherapy, articular cartilage degeneration, muscle contraction, cancer progression and wound healing. Techniques presented include ultrasound and other indentation methods, OCT-based suction measurement, osmetic loading, vibro-ultrasound, and shear wave propagation methods.
History and recent development in soft tissue elasticity measurement. Conventional methods for soft tissue elasticity measurement in vitro. Indentation measurement of soft tissue elasticity. Novel indentation measurement of soft tissue elasticity in vivo. Suction measurement of soft tissue elasticity in vivo. Indirect methods for soft tissue elasticity measurement in vivo. Elasticity imaging and elasticity measurement. Elasticity, nonlinearity, and viscoelasticity of soft tissues. Finite element methods and inverse solutions for elasticity measurement. Clinical applications of soft tissue elasticity measurement in vivo. Conclusions and future perspectives.