Synthetic Gene Network

Modeling, Analysis and Robust Design Methods

By Bor-Sen Chen, Yu-Chao Wang

© 2014 – CRC Press

216 pages | 26 Color Illus. | 20 B/W Illus.

Purchasing Options:
Hardback: 9781466592698
pub: 2014-05-01
US Dollars$129.95
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About the Book

This book develops a rational design and systematic approach to construct a gene network with desired behaviors. In order to achieve this goal, the registry of standard biological parts and experimental techniques are introduced at first. Then these biological components are characterized by a standard modeling method and collected in the component libraries, which can be efficiently reused in engineering synthetic gene networks. Based on the system theory, some design specifications are provided to engineer the synthetic gene networks to robustly track the desired trajectory by employing the component libraries.

Table of Contents

General introduction

Survey of synthetic gene networks

Experimental techniques for engineering synthetic gene networks

Mathematical models and design specifications in synthetic gene networks

Robust synthetic biology designs based on system dynamic methods

Construction of promoter library and RBS library for synthesis of gene networks

Robust synthetic gene network designs based on library-search method

Next-generation synthetic gene network

Subject Categories

BISAC Subject Codes/Headings:
MAT003000
MATHEMATICS / Applied
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics
SCI049000
SCIENCE / Life Sciences / Biology / Molecular Biology
TEC007000
TECHNOLOGY & ENGINEERING / Electrical