1st Edition

Safety Concerns for Herbal Drugs

By Divya Vohora, S. B. Vohora Copyright 2016
    180 Pages 2 B/W Illustrations
    by CRC Press

    Are herbal drugs totally devoid of adverse effects when used alone, as herbal formulations, or in concurrent use with modern medicines? Safety Concerns for Herbal Drugs examines that question and others like it to give you the information you need to judge for yourself the balance between the risks and benefits associated with the therapeutic use of medicinal plants. It stands out from other books by directing your attention to the aspects of safety and toxicity.

    The authors venture into the relatively unexplored (or deliberately hidden) side of the picture. They present a survey of approximately 1500 medicinal plants and herbal products, 59 global (from 27 countries) and 75 Indian examples of toxic and adverse effects and drug interactions. Additionally, they present the current status of regulatory laws and their enforcement in 73 countries to support their contention that such laws and enforcement are inadequate, and that herbal drugs are unscientifically being promoted as totally safe.

    To give you the full picture, the authors go on to examine such issues as danger from large-scale misuse and abuse, self-prescription, substitution, adulteration, concurrent use with modern medicines, hazardous but avoidable drug interactions, risk groups, and present status of drug regulations.

    Introduction
    Herbal Drugs: Wide Usage and Popularity
    Causes for Alienation from Modern Medicine
    Questions and Aims of the Study

    Toxicity and Adverse Effects of Herbal Drugs
    Introduction
    Incidence
    Classification and Factors Affecting Herbal Toxicity
    Risk Groups

    Global Picture

    The Indian Scene
    Introduction
    Single Plants
    Formulations

    Regulatory Aspects
    Introduction
    Angola
    Antigua and Barbuda
    Argentina
    Armenia
    Australia
    Austria
    Azerbaijan
    Bangladesh
    Belarus
    Belgium
    Benin
    Bhutan
    Botswana
    Brazil
    Burkina Faso
    Bulgaria
    Burundi
    Cameroon
    Canada
    Central African Republic
    Chad
    China
    Comoros
    Congo
    Czech Republic
    Denmark
    Ethiopia
    Equatorial Guinea
    Estonia
    Finland
    France
    Georgia
    Germany
    Ghana
    Greece
    Guinea
    Hungary
    Iceland
    India
    Indonesia
    Iran
    Ireland
    Israel
    Japan
    Kenya
    Korea
    Maldives
    Mali
    Mauritius
    Myanmar
    Nepal
    Netherlands
    Nigeria
    Norway
    Poland
    Portugal
    Romania
    Russia
    South Africa
    Spain
    Sri Lanka
    Sweden
    Switzerland
    Tajikistan
    Thailand
    Turkey
    Uganda
    Ukraine
    United Kingdom
    United Republic of Tanzania
    United States
    Uzbekistan
    Zambia

    Critical Appraisal of the Available Data

    Biography

    Dr. Divya Vohora, M.Pharm., Ph.D., is a professor of pharmacology and in charge of the pharmaceutical medicine program for the Faculty of Pharmacy, Jamia Hamdard at New Delhi, India. She also is the assistant dean of Students’ Welfare. She has more than 17 years of teaching and research experience and has published 90 publications (including 2 books, 5 book chapters, 21 reviews, and 62 research papers) in reputed national and international journals with more than 700 citations. Her major areas of interest are central nervous system (CNS) pharmacology (with an emphasis on epilepsy, neurodegenerative disorders, and cognitive functions), osteoporosis, histamine, and clinical pharmacology.

    Shashi B. Vohora, M.V.Sc., Ph.D., D.Sc., retired as a professor and head of the Department of Medical Elementology and Toxicology, Hamdard University, New Delhi. Earlier, he worked for the Indian Council of Medical Research at the Post-Graduate Institute of Medical Education and Research, Chandigarh, Lady Hardinge Medical College, New Delhi; and later for the Institute of History of Medicine and Medical Research, New Delhi. He was an honorary project officer in the Drug Standardization Research Unit of the Central Council for Research in Unani Medicine at New Delhi. He has over 30 years of teaching, research, and editing experience with more than 200 research publications, including 18 books.

    "Professors Divya Vohora and S.B. Vohora deserve our thanks for bringing out this very useful and informative book which will undoubtedly help in the rational use of herbal products."
    —Prof. Ranjit Roy Chaudhury, National Professor of Pharmacology; Advisor, Dept. of Health and Family Welfare, Govt. of National Capital Territory of Delhi, from the Foreword