Recent advances in genetic methodology are providing important aetiological and developmental information to the growing literature on Attention Deficit Hyperactivity Disorder (ADHD) and related conditions. Attention, Genes and ADHD is the first book to review and integrate both behaviour-genetic and molecular-genetic advances in this area. It brings together international researchers to show how modern techniques may be applied to the investigation of ADHD, and reviews current findings in the field of ADHD and related conditions.
The book looks at the application of behaviour genetic approaches to twin studies, and reviews diagnostic to ADHD, the relationships between reading, spelling and ADHD, and family and genetic influences on speech and speech and language.
Chapters go on to consider the overlaps between ADHD, Oppositional Defiant Disorder and Conduct Disorder and to explore the environmental and genetic influences among these disorders. The neurobiological and genetic relationship between ADHD and Tourette's Disorder is also examined. The book reviews recent advances in molecular genetics - in particular a discussion of Fragile X as a model for a single single gene effects on ADHD, and the application of genetic methods and approaches to the study of candidate genes. Finally, the implications for education and intervention are discussed, and current and future roles of gentic studies of ADHD are explored, as well as implications of the sequencing of the human genome for child psychiatry.
Preface. Levy, Introduction. Hay, McStephen, Levy, Introduction to the Genetic Analysis of Attentional Disorder. Levy, McStephen, Hay, The Diagnostic Genetics of ADHD Symptoms and Subtypes. Hay, McStephen, Levy, The Developmental Genetics of ADHD Lewis, Familial and Genetic Bases of Speech and Language Disorders. Stevenson, Comorbidity of Reading/Spelling Disability and ADHD. Waldman, Rhee, Levy, Hay, Causes of the Overlap Among Symptoms of ADHD, Oppositional Defiant Disorder, and Conduct Disorder. Rhee, Waldman, Levy, Hay, Aetiology of the Sex Difference in the Prevalence of DSM-III-R ADHD: A Comparison of Two Models. Zametkin, Ernst, Cohen, Singel Gene Studies of ADHD. Barr, Swanson, Kennedy, Molecular Genetics of ADHD. Fredine, Lynch, Hurst, Alsobrook II, The Genetic Relationship Between ADHD and Gilles de la Tourette Syndrome. Hay, Levy, Implications of Genetic Studies of Attentional Problems for Education and Intervention. Rutter, Child Psychiatry in the Era Following Sequencing the Genome. Conclusions. References.