ESMO Handbook of Cancer in the Senior Patient

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Paperback: 9781841847092
pub: 2010-05-20
US Dollars$83.95
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About the Book

The incidence of cancer in senior patients has been increasing worldwide. This book reflects the state of the art in the management of senior adults with cancer. The contributors discuss epidemiology, evaluation, surgical and radiotherapy treatment, hormonal and cytotoxic treatment, and specific cancers such as lung, breast, colorectal, prostate, bladder, gynecological, and renal cell cancer. The book also examines psychological, social, and ethical aspects, as well as the role of the multidisciplinary team. Designed to help clinicians with the delicate decision-making process, it should lead to the best therapy adapted not only to the disease but also the patient.

Table of Contents

Introduction

Defining the Elderly

Biology of Aging and Changes in Organ Function

Changes in Cognition

Cancer and Aging

Clinical Aspects

Further Reading

Cancer Epidemiology

Introduction

Population Demographics

Cancer Demographics

Society-Related Problems

Conclusions

Further Reading

Evaluation of the Senior Cancer Patient: Comprehensive Geriatric Assessment and Screening Tools for the Elderly

Introduction

Short Screening Tools

The Vulnerable Elders Survey 13

MGA Packages

Further Reading

Frailty in the Elderly

Frailty in the Elderly

The Impact of Frailty on Cancer

Assessment of Frailty

Conclusion

Further Reading

Surgical Treatment

Introduction

Indications for Surgery

Patients Selection

Outcomes

Survival

Palliation

Side Effects

Conclusion

Further Reading

Radiotherapy in the Elderly Cancer Patient

Indications for Radiotherapy in the Elderly

Side Effects of Radiotherapy in the Elderly (Acute and Late)

Efficacy and Outcome of Radiotherapy in the Aging

Palliative Setting: Toxicity and Efficacy Ratio

Curative Setting: Combinations of Chemotherapy and Radiotherapy

Selection Criteria for Radiotherapy in the Elderly

Conclusions

Further Reading

Hormonal Anticancer Treatment in the Senior Cancer Patient

Introduction

Breast Cancer

Prostate Cancer

Further Reading

Cytotoxic and Targeted Anticancer Treatment in the Senior Cancer Patient

Introduction

Chemotherapy in Senior Adults

Targeted Therapies in Senior Adults

Further Reading

Treatment of Lymphoma in the Elderly Population

Introduction

Diagnosis and Prognosis

Treatment

Conclusions

Further Reading

Management of Myeloproliferative Diseases in Senior Patients

Diagnosis and Classification of Myeloproliferative Disorders

Treatment Strategies of MPD in the Senior Patient

Conclusions

Future Outlook

Further Reading

Myelodysplastic Syndromes in the Senior Patient

The Relevance of Myelodysplastic Syndromes in the Elderly

Classification and Risk Scoring in MDS

Age-Adjusted Models and Assessment in Elderly MDS Patients

Treatment Options in Elderly MDS Patients

Future Perspectives

Further Reading

Breast Cancer in the Senior Patient

Introduction

Early Breast Cancer

Metastatic Breast Cancer

Conclusions

Further Reading

Lung Cancer in the Elderly

Introduction

Early Non–Small Cell Lung Cancer in the Elderly

Advanced Non–Small Cell Lung Cancer in the Elderly

Small Cell Lung Cancer in the Elderly

Palliative Treatment in Elderly Lung Cancer Patients

Conclusion

Further Reading

Colorectal Cancer

Introduction

Adjuvant Chemotherapy

Metastatic Disease

Conclusion

Further Reading

Prostate Cancer

Introduction and General Background

Treatment of Localized Prostate Cancer in Senior Adult Patients

Treatment of Metastatic Prostate Cancer in Senior Adult Patients

Conclusion

Acknowledgments

Further Reading

Bladder Cancer

Incidence and Mortality

Etiology and Risk Factors

Pathology

Natural History and Tumor Biology

Signs and Symptoms

Imaging, Cystoscopy, and Urinary Cytopathology

Staging

Treatment of NMIBC

Surgical Treatment

Radiotherapy

Organ-Sparing Treatments

Systemic Chemotherapy

Prognosis of BC

Follow-Up

Further Reading

Gynecological Cancer in the Senior Patient

Introduction

Cervical Cancer

Uterine Cancer

Special Types of Endometrial Malignancy

Vaginal Cancer

Vulvar Cancer

Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer

Conclusion

Further Reading

Head and Neck Cancer in the Elderly

Introduction

Surgery

Radiotherapy

Chemotherapy

Targeted Therapies

Conclusion

Further Reading

Renal Cell Cancer

Introduction

Surgery in the Senior Cancer Patient

Systemic Therapy of Metastatic Renal Cell Carcinoma in the Senior Cancer Patient

Patient-Focused Approach

Conclusion

Further Reading

Psychological Problems in Older Cancer Patients

Introduction

Depression

Anxiety

Conclusions

Further Reading

Social and Ethical Aspects

Introduction

Respect

Admiration

Attention

Information

Protection

Diagnosis

Care

Time

Caution

Freedom

Further Reading

The Role of the Multidisciplinary Team

Introduction

The Assessment of Age

Polypharmacy

Management of the Caregiver

Function of the Team

Conclusions and Perspectives

Further Reading

About the Series

European Society for Medical Oncology Handbooks

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MED032000
MEDICAL / Geriatrics
MED062000
MEDICAL / Oncology