Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs and analyses used at different stages of the drug…
Hardback – 2018-08-13
Chapman and Hall/CRC
Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint. Traditional cancer trial designs with…
Hardback – 2018-06-18
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
This edition is a reprint of the second edition published in 2000 by Brooks/Cole and then Cengage Learning. Principles of Biostatistics is aimed at students in the biological and health sciences who wish to learn modern research methods. It is based on a required course offered at the Harvard…
Hardback – 2018-02-16
Chapman and Hall/CRC
Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been…
Paperback – 2017-09-12
Chapman and Hall/CRC
Praise for the Second Edition: "… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size…
Hardback – 2017-08-30
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against…
Hardback – 2017-06-27
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site…
Hardback – 2017-05-17
CRC Press
Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it …The…
Hardback – 2017-05-03
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The…
Hardback – 2017-02-16
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and…
Hardback – 2016-12-20
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for…
Paperback – 2016-11-16
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series
Get Up to Speed on Many Types of Adaptive Designs Since the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second…
Paperback – 2016-10-14
Chapman and Hall/CRC
Chapman & Hall/CRC Biostatistics Series