This book provides information regarding three major aspects of Aβ metabolism: generation from its precursor, degradation within the brain, and transport out of the brain. It is useful for graduate students, post-doctoral fellows, and scientists both in this and other disciplines.
Beta-secretase M. Citron
Alpha-secretases S. Ishiura
ADAM 10/alpha secretase and presenilins/gamma secretase in APP processing and notch signaling D. Hartmann
Gamma-secretase and presenilin M. Wolfe
Biochemistry of gamma-secretase (tentative title) S. Sinha
Presenilin and intracellular protein transport Degradation of Abeta by neprilysin T.C. Saido
Degradation of Abeta by endothelin-converting enzyme C. Eckman
Degradation of Abeta by insulin-degrading enzyme Lipid raft and Abeta metabolism T. Golde
Lipid raft and Abeta accumulation M. Morishima-Kawashima and Y. Ihara
Transport-dependent clearance of Abeta B. Zlokovic
Abeta vaccination C. Lemere
Biography
Saido, Takaomi Comings
