1st Edition

A Holistic Approach to Organic Synthesis

By Philip Garner Copyright 2024
186 Pages 60 Color & 142 B/W Illustrations
by CRC Press

186 Pages 60 Color & 142 B/W Illustrations
by CRC Press

186 Pages 60 Color & 142 B/W Illustrations
by CRC Press

Synthesis is one of the distinguishing features of chemistry as a science. It is the synthetic chemist who uses their intimate understanding of molecular structure and properties to produce materials of great value to society. Thus, it is important for students of chemistry to study synthesis and acquire a working knowledge that enables them to address the following question: given a specific... Read more

Chapter 1 A Simple Holistic Approach to Planning a Synthesis

Chapter 2 Vying for Control: The Synthesis of Reserpine and Quinine

Chapter 3 A Helping Hand from Nature? Bioinspired Synthesis and Semi-synthesis

Chapter 4 Prostaglandins and Triquinanes: Fertile Ground for Method Development

Chapter 5 Polyketide Synthesis: The Challenge of Acyclic Stereocontrol

Biography

Philip Garner received his Ph.D. degree from the University of Pittsburgh under the guidance of (the late) Paul Dowd. This was followed by postdoctoral training in Paul Grieco’s laboratory at Indiana University. In 1983, he took up his first faculty position at the Illinois Institute of Technology in Chicago. He moved to Case Western Reserve University in Cleveland, Ohio in 1985 where he established a research program that focused on methodology for the synthesis of bioactive molecules. In 2007, he moved across the country to join the Department of Chemistry at Washington State University. Over the course of his career, Dr. Garner has trained more than fifty undergraduate researchers, graduate students, and postdoctoral fellows. He has published over 100 papers. His scientific accomplishments include the development of a widely used serinal derivative that has come to bear his name. He currently holds the rank of Professor Emeritus.

A Holistic Approach to Organic Synthesis by Professor Phil Garner is an excellent approach
to teaching the intricacies of synthesizing organic molecules. Classic syntheses are provided along
with pertinent reactions in a pedological approach that students will find both useful and inspiring.
Tutorials are provided to reinforce the approach. I highly recommend this book for both senior
undergraduate and graduate level courses.

- Michael B. Smith, Professor Emeritus, The University of Connecticut (March, 2024)