1st Edition

Acne and Its Therapy

Edited By Guy F. Webster, Anthony V. Rawlings Copyright 2007
    328 Pages 49 Color & 189 B/W Illustrations
    by CRC Press

    Addressing one of the most commonly encountered conditions seen by the dermatologist, this source analyzes the pathophysiology, evaluation, diagnosis, clinical features, and control of acne. With full-color illustrations, this source delves into the available treatment options for difficult cases of acne and scarring and provides expert discussions of management regimens including topical and systemic therapies, laser treatments, and new medications.

    Overview of the Pathogenesis of Acne.  Cell Biology of the Pilosebaceous Unit.  Sebum Secretion and Acne.  Molecular Biology of Retinoids and Their Receptors.  Molecular Biology of Peroxisome Proliferator Activated Receptors in Relation to Sebaceous Glands and Acne.  Antimicrobial Peptides and Acne.  Hormonal Influences in Acne.  Antimicrobial Therapy in Acne.  Topical Retinoids.  Phototherapy and Laser Therapy of Acne.  Benzoyl Peroxide and Salicylic Acid Therapy.  Treating Acne with Octadecenedioic Acid.  The Effect of Sphingolipids as a New Therapeutic Option for Acne Treatment.  5-alpha Reductase and Its Inhibitors.   Sebum: Physical-Chemical Properties, Macromolecular Structure, and Effects of Ingredients.  Targeted Delivery of Actives from Topical Treatment Products to the Pilosebaceous Unit.  Topical Theraoy and Formulation Principles.  In Vitro Models for the Evaluation of Anti-acne Technologies.


    Guy F. Webster, Anthony V. Rawlings