1st Edition

Addiction and Neurodegenerative Disorders Unraveling the Nexus

Edited By Samer El Hayek Copyright 2026
246 Pages 1 Color & 2 B/W Illustrations
by CRC Press

246 Pages 1 Color & 2 B/W Illustrations
by CRC Press

The brain regions and neuronal processes that underlie addiction extensively overlap with those needed for cognitive functions, including learning, memory, and reasoning. Addiction negatively impacts cognitive functions, making it more challenging to maintain abstinence and potentially leading to progression into neurodegenerative disorders. Furthermore, individuals living with neurodegenerative... Read more

1. Animal Models of Substance Use and Neurodegeneration  

Amine Larnaout, Youssef Ernez, Rania Lansari, Wahid Melki  

 

2. Alzheimer's Disease and Drug Addiction: A Global and SubSaharan African Perspective  

Joy Louise GumikirizaOnoria, Dennis Buwembo, Rita Nassanga, Kamada Lwere  

 

3. Frontotemporal Dementia and Drug Addiction  

Victor Olufolahan Lasebikan, Victor Makanjuola, Morufat Abosede Alabi, Tiwatayo Olufolahan Lasebikan, Oluremi Oladipo Oladele, Oyeyemi Afolabi  

 

4. Huntington's Disease, Amyotrophic Lateral Sclerosis, and Addiction  

Yara Ghanem, Mounir Fakhouri, Karl Khalil, Mario Eid  

 

5. Parkinson's Disease and Addiction  

Wassim Hassan, Noreen Hassan, Ahmad Hassan, Luke Petry  

 

6. Alcohol and Neurogenerative Disorders  

Victor Olufolahan Lasebikan, Victor Makanjuola, Tiwatayo Olufolahan Lasebikan, Oluremi Oladipo Oladele, Morufat Abosede Alabi, Oyeyemi Afolabi  

 

7. Cannabis and Neurodegenerative Disorders  

Elie Atallah, Sahar Obeid, Myriam ElKhoury Malhame, Michel Sfeir  

 

8. Opioid Use and Neurodegenerative Disorders   

Abhishek Ghosh, Ankita Chattopadhyay, Shinjini Choudhury  

 

9. Sedative, Hypnotic, and Anxiolytic Use and Neurodegenerative Disorders  

Kirtika Aggarwal, Awanish Mishra, Ramdas Ransing, Samer El Hayek  

 

10. Stimulants and Neurodegenerative Disorders  

Sarah El Halabi, Ismail Deniz, Bita Vahdani, Odel Zadeh, Sanya Virani  

 

11. Tobacco and Neurodegenerative Disorders   

Celal Yesilkaya, Serkan Turan  

 

12. Behavioral Addictions in Neurodegenerative Disorders  

Shyam Sundar Kanagarajan, Kavitha Parthiban  

 

13. Addressing Addiction in Individuals with Neurodegenerative Disorders: Approach, Screening, and Management  

Karine Kahil, Lea Daou, Hala Itani, Rawan Koleilat, Farid Talih  

 

14. PsychedelicInspired Approaches for Treating Neurodegenerative Disorders  

Mahdieh Saeidi, Victor PereiraSanchez, Maryam Noroozian, Mohammadreza Shalbafan, Mona Salehi, Sasidhar Gunturu  

 

15. Environmental Factors and Challenges in Managing Addiction and Neurodegenerative Disorders  

Ruta Karaliuniene, Margaret Ojeahere, Chonnakarn Jatchavala, Sachin Nagendrappa, Ramyadarshni Vadivel, Bita Vahdani  

 

16. Challenges of Neurodegenerative and Substance Use Disorders in Low and MiddleIncome Countries   

Joy Louise GumikirizaOnoria, Rita Nassanga, Dennis Buwembo, Kamada Lwere  

 

17. Ethical and Legal Considerations   

Chadi Antoun, Ahmad Sabalbal, Noreen Hassan, Tala Diab, Farid Talih 

Biography

Dr. Samer El Hayek, MD, is a specialist psychiatrist at the American Center for Psychiatry and Neurology, Dubai, United Arab Emirates, and an adjunct assistant professor of clinical psychiatry at the American University of Beirut Medical Center (AUBMC), Beirut, Lebanon. An accomplished adult and addiction psychiatrist, Dr. El Hayek brings a robust clinical, academic, and research background to his work.

Dr. El Hayek completed a fellowship in addiction psychiatry at the University of Miami-Jackson Health System in Miami, Florida, United States, in 2022, following a clinical psychiatry residency at AUBMC. With over three years of focused experience in addiction psychiatry, Dr. El Hayek has developed expertise in managing dual diagnoses and implementing patient-centered, multidisciplinary approaches. His clinical practice is informed by his extensive work with individuals from various cultural and socioeconomic backgrounds, underscoring his global perspective and dedication to reducing mental health disparities.

A passionate researcher and thought leader, Dr. El Hayek has authored over 85 peer-reviewed publications, with research interests spanning global mental health, addiction, and stigma. His scholarly contributions have been cited more than 2,000 times, earning him an h-index of 22 by 2024. His research achievements were recognized by his induction into Sigma Xi, The Scientific Research Honor Society, in 2023. He is also the recipient of several awards, including the 2023 Yearly Research Contribution Award from the Erada Center for Treatment and Rehabilitation in Dubai, the 2019 Early-Career Psychiatrists Award from the 15th International Congress on Psychiatry at Ain Shams University in Cairo, and the 2019 Asian Federation of Psychiatric Associations Fellowship Award for Young Psychiatrists at the 7th World Congress of Asian Psychiatry in Melbourne, Australia.

Dr. El Hayek is a board member and the Eastern Mediterranean Region representative for the Network of Early-Career Professionals Working in Addiction Medicine (NECPAM). He also holds editorial roles in several scientific journals, including Frontiers in Public Health and Current Psychopharmacology.