1st Edition

Advanced Gene Delivery

Edited By Alain Rolland Copyright 1999
328 Pages
by CRC Press

328 Pages
by CRC Press

A practical resource for everyone involved in the gene therapy field and in the design of effective gene delivery systems, this volume presents an overview and update of recent advances in the field of non-viral methods for the in vivo transfer of therapeutic genes to biological targets using conventional routes of administration. Methods to control the spatial and temporal modulation of gene... Read more
1. Present and Future Status of Gene Therapy 2. DNA Packaging in Non Viral Systems 3. Biological Barriers to Gene Transfer 4. Therapeutic Applications of Lipid-Based Gene Delivery Systems 5. Polycation-based Delivery Systems for Receptor-Mediated Gene Delivery 6. DNA Delivery Systems Based on Synthetic Peptides 7. Expression Plasmids for Non-Viral Gene Therapy 8. Gene Therapy Clinical Trials for Cystic Fibrosis 9. Polymeric Gene Delivery Systems for In Vivo Gene Therapy 10. Intravascular Delivery of Naked Plasmid DNA 11. Cationic Lipid-Based Gene Delivery Systems 12. Gene-based Vaccines 13. Gene Therapy for Cancer: Strategies and Review of Clinical Trials

Biography

Alain Rolland