1st Edition

Advanced MR Neuroimaging From Theory to Clinical Practice

By Ioannis Tsougos Copyright 2018
    240 Pages
    by CRC Press

    238 Pages 84 Color Illustrations
    by CRC Press

    Over the last decade, some of the greatest achievements in the field of neuroimaging have been related to remarkable advances in magnetic resonance techniques, including diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. Such techniques have provided valuable insights into tissue microstructure, microvasculature, metabolism and brain connectivity.

    Previously available mostly in research environments, these techniques are now becoming part of everyday clinical practice in a plethora of clinical MR systems. Nevertheless, despite growing interest and wider acceptance, there remains a lack of a comprehensive body of knowledge on the subject, exploring the intrinsic complexity and physical difficulty of the techniques.

    This book focuses on the basic principles and theories of diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. It also explores their clinical applications and places emphasis on the associated artifacts and pitfalls with a comprehensive and didactic approach.

    This book aims to bridge the gap between research applications and clinical practice. It will serve as an educational manual for neuroimaging researchers and radiologists, neurologists, neurosurgeons, and physicists with an interest in advanced MR techniques. It will also be a useful reference text for experienced clinical scientists who wish to optimize their multi-parametric imaging approach.

    Chapter 1. Diffusion MR Imaging

    Chapter 2. Artifacts and Pitfalls in Diffusion MRI

    Chapter 3. Perfusion MR Imaging

    Chapter 4. Artifacts and Pitfalls of Perfusion MRI

    Chapter 5. Magnetic Resonance Spectroscopy

    Chapter 6. Artifacts and Pitfalls of MRS

    Chapter 7. Functional Magnetic Resonance Imaging (fMRI)

    Chapter 8. Artifacts and Pitfalls of fMRI

    Chapter 9. The Role of Multiparametric MR Imaging – Advanced MR Techniques in the Assessment of Cerebral Tumors.


    Dr. Ioannis Tsougos holds a BSc in Physics and an MSc and a PhD in Medical Physics. Currently, he is an Assistant Professor of Medical Radiation Physics at the Medical School of the University of Thessaly, Larissa, Greece and a Visiting Researcher in the Neuroimaging Division at the Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, UK. He has authored more than 70 research papers and 10 international book chapters. He is a member of the EFOMP, ESR, and ESMRMB.

    "The book entitled "Advanced MR Neuroimaging - From Theory to Clinical Practice" by Professor Ioannis Tsougos represents a smooth and yet comprehensive introduction to four of the most important methods in the field of MR neuroimaging…Professor Tsougos has chosen four advanced MR imaging techniques, namely Diffusion and Perfusion MRI, MR spectroscopy, and functional MRI, to include in his book. These methods are introduced from theoretical basics to clinically relevant aspects and their application in clinical MR neuroimaging routine. These explanations are complemented by a separate chapter for artifacts and pitfalls in each of the four methods…The author starts each section with focus points to raise the reader’s awareness of key features and essential concepts covered, which make it especially for beginners in the field accessible to get oriented…This book can be recommended to researchers and basic scientist making their first steps in neuroimaging. It will also help clinical scientists, who want to extend their knowledge in multi-parametric neuroimaging.
    Although many recent techniques like ASL and resting-state fMRI are included in their corresponding chapters, some of the most recent developments in Diffusion MRI or in other advanced neuroimaging techniques like quantitative susceptibility mapping (QSM) or MR elastography are not covered in the book. However, publishing a complete and educational volume covering the entire spectrum of advanced MR neuroimaging and serving as a reference is a difficult task to accomplish, since this field is highly active and continuously growing. Notwithstanding the above, I can highly recommend this well-illustrated book to all neuroimaging researchers, radiologists and neurosurgeons with interest in advanced MR techniques as well as to students in the medical field."

    — Dr. Daniel Güllmar in European Medical Physics News, Issue 01/2020 (Spring)