1st Edition

Advanced Porous Biomaterials for Drug Delivery Applications

    468 Pages 112 B/W Illustrations
    by CRC Press

    Advanced Porous Biomaterials for Drug Delivery Applications probes cutting-edge progress in the application of advanced porous biomaterials in drug delivery fields. These biomaterials offer promise in improving upon the design, cost, and creation of potent novel drug delivery systems. The book focuses on two categories: nature engineered and synthetic advanced porous biomaterials, with a wide range of low-cost porous biomaterial-based systems that have been used for the delivery of diverse drugs through in vitro/in vivo approaches.

    • Details how advanced porous biomaterial-assisted systems improve essential properties in drug delivery applications
    • Explains how advanced porous biomaterials systems are being used and explored to improve overall performances of drug delivery systems in mitigating a variety of diseases
    • Emphasizes major applications in drug delivery such as controlled release, cancer therapy, and targeted delivery, and with focus on oral, topical, and transdermal applications
    • Focuses on both naturally available and synthetic low-cost advanced porous biomaterials and their role in enhancing important parameters in drug delivery applications
    • Accessible to readers with bio and non-bio backgrounds

    This book is an ideal reference for academics, researchers, and industry professionals in the interdisciplinary fields of biomedicine and biomedical engineering, pharmaceuticals, materials science, and chemistry.

    Part A: Overview of Drug Delivery and Porous Materials. 1. A Brief Overview of Drug Delivery Systems and Significance of Advanced Porous Biomaterials in the Drug Delivery Field. Part B: Natural Porous Materials. 2. Silk Fibroin-Based Drug Delivery Systems. 3. Surface Bioengineering of Nanostructured Diatom Biosilica and Their Applications in Drug Delivery. 4. Different Classes of Nanoclay Materials (Halloysite, Montmorillonite, and Kaolinite) and Their Applications in Controlled Drug Release and Targeted Drug Delivery. 5. Naturally Obtained Zeolites for Drug Delivery Applications. 6. Porous Calcium Carbonate and Calcium Phosphate in Drug Delivery Applications. Part C: Synthetic Porous Materials. 7. Metal-Organic Frameworks (MOFs)-Based Carriers for Tumor Therapy. 8. Covalent Organic Frameworks (COFs) for Drug Delivery Applications. 9. Nanoporous Anodic Alumina (NAA) for Drug Delivery Applications. 10. Electrochemically Nano-engineered Titanium Implants toward Drug Delivery Applications. 11. Porous Silicon for Drug Delivery Applications. 12. Surface Modified Graphene Oxides (GO) for Chemotherapeutic Drug Delivery. 13. Fullerene Derivatives for Drug Delivery Applications. 14. Applications of Carbon Nanotubes in Drug Delivery.


    Mahaveer D. Kurkuri is currently working as Professor and Associate Director at Centre for Research in Functional Materials (CRFM), Jain (Deemed-to-be University), India. He has received his PhD degree in Polymer Chemistry from Karnataka University, Dharwad, India in the year 2003. He worked in various well-known reputed Universities as Post-Doctoral Fellow at KAIST, South Korea (2004-2006), Research Associate, Flinders University, Australia (2006-2008), Research Fellow at University of Adelaide, Australia (2008-2014). Since 2014 he is associated with Jain (Deemed-to-be University), India. He has published >70 papers in peer-reviewed journals with >2630 citations and h-index: 31. His current research interests are drug delivery, water treatment, energy, microfluidics, supramolecular chemistry, biosensors, ion detection, molecular logic gates, and surface chemistry in general to mimic the nature particularly utilizing the understandings in nano and bio areas.

    Dusan Losic is a Professor and Graphene Hub Director at the School of Chemical Engineering and Advanced Materials, University of Adelaide, and leader of Nano research group with 20 researchers. He completed PhD (2003) in Nanoscience and Nanotechnology (Flinders University, Australia) as one of the first PhD in Australia in this field. After 3 years Postdoctoral work at Flinders University in 2007 he received ARC Research Fellowship (5 years) starting his independent research at University of South Australia (Ian Wark Research Institute). In 2012 he received ARC Future Fellowship, and join the University of Adelaide with his research group. His multidisciplinary research involves fundamental, engineering and applied aspects across disciplines of nanotechnology, chemistry, materials science, engineering, medicine and agriculture with focus on engineering of new nano materials, new properties and their applications to address concerning problems in health, environment, agriculture and energy. He published >470 publications in leading journals and conferences including 3 Edited books, 20 book chapters, 300 journal papers, 80 conference papers, 120 conference abstracts and 9 patents, attracting ca 20,500 citations, h-index:78 and 14 journal covers, presented 5 Plenary, 10 key, 20 invited conference lectures, 100 Invited talks and seminars at Universities worldwide. He received ~ $20 M in research funding in last 10 years completing 40 research projects, half involving industry with an outstanding track record in research translation (5 licensing technologies).

    Dr. U. T. Uthappa is currently working as Assistant International Research Professor at School of Chemical Engineering, Yeungnam University, Republic of Korea. He has received his PhD degree in Chemistry from Jain (Deemed-to-be University), India in the year 2020. Prior to joining Yeungnam University, he worked as Post-Doctoral Fellow at Chonnam National University, South Korea (2021-2022). His core research interest lies in the design of novel biomaterials for drug delivery (controlled release and targeted drug delivery) and water treatment applications. He has published >20 papers in peer-reviewed journals with >530 citations and h index: 13. Dr. Uthappa published his research works in high impact journals such as Trends in Analytical Chemistry, Journal of Controlled Release, Applied Surface Science, Chemosphere, Advances in Colloid and Interface Science and ACS Biomaterials Science & Engineering.

    Ho-Young Jung serves as full time Professor for Environment & Energy Engineering Department at Chonnam National University, South Korea. He obtained his Ph.D. in Chemical and Biomolecular Engineering at KAIST in 2007. Prior to joining as Professor in Chonnam National University, South Korea, he worked in various well-known reputed Universities as Post-Doctoral fellow at KAIST (2007-2008), Research Associate at USC (2008-2009), Assistant Professor at Kangwon National University (2009-2012) & Associate Professor at Chonnam National University, South Korea. His research interests include energy storage devices, batteries, membranes, drug delivery & water treatments. He published >90 research papers in internationally recognized peer review journals and >25 patents are added to his credit.