Advances in Clinical Immunology, Medical Microbiology, COVID-19, and Big Data  book cover
1st Edition

Advances in Clinical Immunology, Medical Microbiology, COVID-19, and Big Data

Edited By

Raj Bawa

  • Available for pre-order. Item will ship after December 23, 2021
ISBN 9789814877848
December 23, 2021 Forthcoming by Jenny Stanford Publishing
930 Pages 149 Color & 27 B/W Illustrations

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Book Description

The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, ethics, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research, medicine, engineering, FDA law, intellectual property law, and regulatory science, the series provides a thorough understanding of medicine's potential to address health problems from both the patient’s and the provider's perspectives in a healthcare setting. The range of topics covered, and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine—from basic medical sciences to clinical specialties. Current Issues in Medicine is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The book’s multidisciplinary approach makes it a valuable reference resource for the pharmaceutical industry, academia, and governments globally. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century.Volumes 1 and 2 in this series are focused on current issues in basic medical science, subjects that are fundamental to the practice of medicine. These basic medical science subjects are traditionally taught in the first two years of medical school that precede clinical instruction and training. They provide a core of basic knowledge critical to the success in clinical medicine during rotations through surgery, internal medicine, and the other specialties of medicine. Obviously, knowledge gleaned from these subjects leads to better ways to predict, prevent, diagnose, and treat disease. Specifically, volume 2 covers immunology, microbiology, biostatistics, and big data. Clinical specialties are covered in Volume 3. Volume 4 is directed towards diagnosis and imaging techniques, volume 5 focuses on drug delivery, and volume 6 highlights novel therapeutics and clinical applications.

Table of Contents


Current Immune Aspects of Biologics and Nanodrugs: An Overview
Raj Bawa

Animal Models for Analysis of Immunological Responses to Nanomaterials: Challenges and Considerations
William C. Zamboni, Janos Szebeni, Serguei V. Kozlov, Andrew T. Lucas, Joseph A. Piscitelli, and Marina A. Dobrovolskaia

Human Clinical Relevance of the Porcine Model of Pseudoallergic Infusion Reactions
János Szebeni  and Raj Bawa

Myelin Antigens and Antimyelin Antibodies
Fredrick J. Seil

Advances in the Understanding of Inflammatory Milieu and Its Correlations with Neurological Disorders
Mario Ganau, Sibel Huet, Nikolaos Syrmos, Mohammad Iqbal, Marco Meloni

Role of Ligustrum in Allergic Disease
Priyadharshini Vellore Suresh, Tania Robledo Retana, Blessy M Mani, Ana Paulina Barba de la  Rosa, and Luis M Teran

Protective or Detrimental? Understanding the Role of Host Immunity in Leishmaniasis
Camila dos Santos Meira and Lashitew Gedamu

Personalized Nanomedicines for Treatment of Autoimmune Disease
Cheng Lin, Huihua Ding, Congcong Li, Nan Shen, Aimin Zhao, Matthias Bartneck


Forecasting the Novel Coronavirus COVID-19
Fotios Petropoulos and Spyros Makridakis
COVID-19 Pandemic: Implications for Dental Practitioners
Najla Dar Odeh, Hamzah Babkair, Shaden Abu-Hammad, Sary Borzangy, Abdalla Abu-Hammad  and Osama Abu-Hammad

The Ocular Surface and the Coronavirus Disease 2019: Does a Dual ‘Ocular Route’ Exist?
Pietro Emanuele Napoli, Matteo Nioi, Ernesto d’Aloja, and Maurizio Fossarello

We Do Not Eat Alone: Formation and Maturation of the Oral Microbiota
Luca Fiorillo

Could Environment Affect the Mutation of H1N1 Influenza Virus?
Dong Jiang, Qian Wang, Zhihua Bai, Heyuan Qi, Juncai Ma, Wenjun Liu Fangyu Ding, and Jing Li

Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?
Cristian-Marian Popescu, Aurora Livia Ursache, Gavriela Feketea, Corina Bocsan, Laura Jimbu, Oana Mesaros, Michael Edwards, Hongwei Wang, Iulia Berceanu, Alexandra Neaga, and Mihnea Zdrenghea

Knowledge, Perceptions and Practices of Community Pharmacists towards Antimicrobial Stewardship: A Systematic Scoping Review
Sajal K. Saha, Chris Barton, Shukla Promite, and Danielle Mazza

Where Cancer and Bacteria Meet
Alexandra Merlos, Ricardo Perez-Tomás, José López-López, and Miguel Viñas

A Novel Cohort Analysis Approach to Determining the Case Fatality Rate of COVID-19 and Other Infectious Diseases
Charit Samyak Narayanan

ISIDOG Recommendations Concerning COVID-19 and Pregnancy
Francesca Donders, Risa Lonnée-Hoffmann, Aristotelis Tsiakalos, Werner Mendling, José Martinez de Oliveira, Philippe Judlin, Fengxia Xue, Gilbert G. G. Donders, and ISIDOG COVID-19 Guideline Workgroup

The Unmet Medical Need for Trypanosoma cruzi-Infected Patients: Monitoring the Disease Status
Maan Zrein and Eric Chatelain

Present and Future of Carbapenem-Resistant Enterobacteriaceae (CRE) Infections
Beatriz Suay-García and María Teresa Pérez-Gracia

Human Plague: An Old Scourge That Needs New Answers
Xavier Vallès, Nils Chr. Stenseth, Christian Demeure, Peter Horby, Paul S. Mead, Oswaldo Cabanillas, et al.


Human Brain/Cloud Interface
Nuno R. B. Martins, Amara Angelica, Krishnan Chakravarthy, Yuriy Svidinenko, Frank J. Boehm, Ioan Opris, Mikhail A. Lebedev, Melanie Swan, Steven A. Garan, Jeffrey V. Rosenfeld, Tad Hogg, and Robert A. Freitas Jr

Artificial Intelligence in Drug Discovery: What Is New, and What Is Next?
Francesca Lake

Now the Future, We See Our Dreams: Artificial Intelligence in Drug Discovery
Rae Lawrence

How Big Data and Artificial Intelligence Can Help Better Manage the COVID-19 Pandemic
Nicola Luigi Bragazzi, Haijiang Dai, Giovanni Damiani, Masoud Behzadifar, Mariano Martini, and Jianhong Wu

Paradigm Shift in Medicinal Chemistry towards Data-Driven Approaches
Jürgen Bajorath

The Importance of Proper Statistical Methods in Developing  Robust Predictive Models Using Chemodescriptors and Biodescriptors in the Twenty First Century
Subhash C. Basak
Fit-for-Purpose?’—Challenges and Opportunities for Applications of Blockchain Technology in the Future of Healthcare
Tim K. Mackey, Tsung-Ting Kuo, Basker Gummadi, Kevin A. Clauson, George Church, Dennis Grishin, Kamal Obbad, Robert Barkovich, and Maria Palombini

Feasibility of a mHealth Approach to Nutrition Counseling in an Appalachian State
Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Dustin M. Long, Treah S. Haggerty, Mathew Weimer, Joseph Golden, Mary Ann Maurer, Jill D. Cochran, Tracy Hendershot, Stacey L. Whanger, Jay D. Mason and Sally L. Hodder


A Future Perspective for Regenerative Medicine: Understanding the Concept of Vibrational Medicine
Kavita Beri

Burnout and Doctors: Prevalence, Prevention and Intervention
Shailesh Kumar

Fungal Diseases as Neglected Pathogens: A Wake-Up Call to Public Health Officials
Marcio L. Rodrigues and Joshua D. Nosanchuk

Survey on Open Peer Review: Attitudes and Experience amongst Editors, Authors and Reviewers
Tony Ross-Hellauer, Arvid Deppe, and Birgit Schmidt

The Common Ground of Open Access and Interdisciplinarity
Patrick Gamsby

China’s Illegitimate Game of Intellectual Property Theft
Raj Bawa

Animals and Patents: The Mouse That Went to Harvard!
Raj Bawa

Simultaneous Dengue and COVID-19 Epidemics: Difficult Days Ahead
Mathieu Nacher, Maylis Douine, Mélanie Gaillet, Claude Flamand, Dominique Rousset, Cyril Rousseau, Chedli Mahdaoui, Stanley Carroll, Audrey Valdes, Nathalie Passard, Gabriel Carles, Félix Djossou, Magalie Demar, and Loïc Epelboin

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Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, Virginia, USA, that he founded in 2002. Trained as a biochemist and microbiologist, he is an inventor, entrepreneur, professor, and registered patent agent licensed to practice before the US Patent & Trademark Office. He is currently a scientific advisor to Teva Pharmaceutical Industries, Ltd. (Israel), a visiting research scholar at the Pharmaceutical Research Institute of Albany College of Pharmacy (Albany, New York), and vice president and chief intellectual property officer at Guanine, Inc. (Rensselaer, New York). He has previously served as a principal investigator of National Cancer Institute SBIRs and continues to be a scientific reviewer for both the NIH and NSF. He recently (2017–2019) served as principal investigator of a CDC grant to develop an assay for Carbapenem-resistant Enterobacteriaceae. Since 2004, he has been an adjunct professor in the biology department and the Extended Learning Institute of Northern Virginia Community College (Annandale, Virginia), where he also teaches human anatomy and physiology to pre-nursing students. In the 1990s, Dr. Bawa held various positions at the US Patent & Trademark Office, including primary patent examiner from 1996–2002. Previously, he was an adjunct professor at Rensselaer Polytechnic Institute in Troy, New York from 1998–2018, where he received his doctoral degree in three years (biophysics/biochemistry).

Dr. Bawa is a life member of Sigma Xi, co-chair of the nanotech and precision medicine committees of the American Bar Association (2015–2021), and founding director of the American Society for Nanomedicine (founded in 2008). He has authored over 100 publications, co-edited 9 texts, and serves on the editorial boards of numerous peer-reviewed journals, including serving as an associate editor of Nanomedicine (Elsevier). Some of Dr. Bawa’s awards include the Innovations Prize from the Institution of Mechanical Engineers, UK (2008); Appreciation Award from the US Undersecretary of Commerce, Washington, DC (2001); the Key Award from Rensselaer’s Office of Alumni Relations (2005); and Lifetime Achievement Award from the American Society for Nanomedicine (2014).