Advances in Particle Therapy : A Multidisciplinary Approach book cover
1st Edition

Advances in Particle Therapy
A Multidisciplinary Approach

ISBN 9780367571559
Published June 30, 2020 by CRC Press
298 Pages

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Book Description

Hadron therapy is a groundbreaking new method of treating cancer. Boasting greater precision than other therapies, this therapy is now utilised in many clinical settings and the field is growing. More than 50 medical facilities currently perform (or are planned to perform) this treatment, with this number set to double by 2020. This new text covers the most recent advances in hadron therapy, exploring the physics, technology, biology, diagnosis, clinical applications, and economics behind the therapy. Providing essential and up-to-date information on recent developments in the field, this book will be of interest to current and aspiring specialists from a wide range of backgrounds.


  • Multidisciplinary approach: explores the physics, IT (big data), biology, clinical applications from imaging to treatment, clinical trials, and economics associated with hadron therapy

  • Contains the latest research and developments in this rapidly evolving field, and integrates them into the current global challenges for radiation therapy  

  • Edited by recognised leaders in the field, including the co-ordinator of ENLIGHT (the European Network for Light Ion Hadron Therapy), with chapter contributions from international leading experts in the field

Table of Contents

From Röntgen Rays to Carbon Ion Therapy: The Evolution of Modern Radiation Oncology. Radiobiology and Hadron Therapy: What Do We Know and What Do We Need to Know?  Challenges Surrounding RBE for Particle Therapy: Where Do We Go from Here? Advances in Beam Delivery Techniques and Accelerators in Particle Therapy. Requirements for setting up a Particle Therapy Center. Imaging and Particle Therapy: Current Status and Future Perspectives. Why particle therapy rather than photon therapy or how to integrate the decision into multimodal management. Role of Multidisciplinary Collaborative Network for Advancing Cancer Therapy. Long-term outcomes and prognostic factors in patients with indications for particle therapy in sarcomas. Proton therapy for pediatric patients. NTCP Reduction in Advanced Head and Neck Cancer Patients Using Proton Therapy. The model-based approach to select patients for proton therapy and to validate its added value. Overview of Carbon-Ion Radiotherapy in Japan. Particle therapy clinical trials: perspectives from Europe, Japan and USA. Role of Particle Therapy in Future Radiotherapy practice. Health Economics: Cost, Cost-Effectiveness and Budget Impact of Particle Therapy. Big data-based Decision Support systems for Hadrontherapy. Cern Collaborations in Hadron Therapy and Future Accelerators. Addressing Global Challenges for Radiation Therapy: From “C” to shining “C” (Cobalt to Carbon) and the “Radiation Rotary”.

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Manjit Dosanjh  is the co-ordinator of the Technology Transfer Network and Biomedical Applications in the Education and Technology Transfer Division  at CERN and a Health Consultant for the Forum for Health. She is also the co-ordinator of ENLIGHT (the European Network for Light Ion Hadron Therapy).

Jacques Bernier is the Medical Director of the Oncology Department of the Clinique de Genolier and the Integrated Center for Radiation Oncology of Eaux-Vives in Geneva. He is also Course Director at the European School of Oncology.


"This book is recommended for individuals coming into the field of particle therapy as well as those curious enough to want to learn about this topic without having to master dense particle physics material."

Alonso N Gutierrez, PhD, MBA (Miami Cancer Institute)