This innovative book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it will help mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to underlying concepts at the heart of personalized medicine - pharmacogenomics, targeted therapies and individualized diagnosis and treatment - and shows how, with the advent of genomic technologies, clinicians will have the capability to predict and diagnose disease more efficiently. Advocating a patient-centred approach at the heart of care, this introduction to personalized medicine, the science behind it, its economic effects, its effects upon patients and its overall implications for society will be invaluable to clinicians, to healthcare providers and to patients.
Acknowledgements. Preface. Introduction: Biomedical Innovation and Policy in the 21st Century. The Rise of Genomics and Personalized Medicine. Patient Narratives: Personalized Medicine in the Field. Alliances: Knowledge Infrastructures and Precision Medicine. Great Strides in Precision Medicine: Personalized Oncology and Molecular Diagnostics. Personalized Medicine’s Impact on Disease. The Genome in the Clinic: Diagnosis, Treatment and Education. A New Set of Clinical Tools for Physicians. The Regulatory Landscape. Translational Personalized Medicine: Molecular Profiling, Druggable Targets and Clinical Genomic Medicine. The Economics of Personalized Medicine. Moral and Ethical Issues: Claims, Consequences, and Caveats. Conclusion.