1st Edition

Alginates Versatile Polymers in Biomedical Applications and Therapeutics

Edited By Md Saquib Hasnain, Amit Kumar Nayak Copyright 2019
    646 Pages 8 Color & 133 B/W Illustrations
    by Apple Academic Press

    646 Pages 8 Color & 133 B/W Illustrations
    by Apple Academic Press

    646 Pages 8 Color & 133 B/W Illustrations
    by Apple Academic Press

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    This new volume explores the latest research on the use of alginate as a biopolymer in various biomedical applications and therapeutics. The uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for the biomedical applications and therapeutics.

    Alginate, a biopolymer of natural origin, is of immense interest for its variety of applications in pharmaceuticals (as medical diagnostic aids) and in materials science. It is the one of the most abundant natural biopolymers and is considered an excellent excipient because of its non-toxic, stable, and biodegradable properties. Several research innovations have been made on applications of alginate in drug delivery and biomedicines. There needs to be a thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields, and this volume offers an abundance of information toward that end.

    1. Alginates: Source, Chemistry and Properties

    Mithilesh Yadav and Younes Ahmadi

    2. Recent Advances of Alginates as Material for Biomedical Applications

    Milan Milivojevic, Ivana Pajic-Lijakovic, and Branko Bugarski

    3. Alginates: Hydrogels, their Chemistry and Applications

    Verónica Elena Manzano et al.

    4. Alginate Based Hydrogels: Synthesis, Characterization and Biomedical Application

    Vandana Singh and Angela Singh

    5. Chemically Modified Alginates for Advanced Biomedical Applications

    Ibrahim M. El-Sherbiny et al.

    6. Bionanocomposites of Alginates, their Chemistry and Applications

    Nancy L. García et al.

    7. Alginate and its Applications in Tissue Engineering

    Dilshad Qureshi et al.

    8. Alginate-Based Scaffolds in Bone Tissue Engineering Applications

    S. Viji Chandran, V. Sanjay, and N. Selvamurugan

    9. Alginate-Properties, Pharmaceutical and Tissue Engineering Applications

    K. S. Joshy, S. Snigdha, and Sabu Thomas

    10. Alginate: Drug Delivery and Application

    Gautam Singhvi et al.

    11. Chemical and Physical Modifications of Alginate to Improve its use as Carriers in Delivery Systems

    Gabriela Valladares, Karina Bierbrauer, and Miriam Strumia

    12. Updates on Alginate-Based Interpenetrating Polymer Networks for Sustained Drug Release

    Ibrahim M. El-Sherbiny and Kholoud Arafa

    13. Alginate Nanoparticles

    Isra Dmour and And Mutasem Taha

    14. Alginate Based Nanocarriers in Modern Therapeutics

    Vandana Singh and Angela Singh

    15. Alginate Based Composites in Drug Delivery Application

    Ankita Tiwari et al.

    16. Hydroxyapatite-Alginate Composites in Drug Delivery

    Sitansu Sekhar Nanda et al.

    17. Alginate-Based Gastro-Intestinal Tract Drug Delivery Systems

    Sougata Jana, Kalyan Kumar Sen, and Sabyasachi Maiti

    18. Alginate Hydrogels as Colon-Targeted Drug Delivery System

    Pramendra Kumar and Deepak Kumar

    19. Alginate Carriers for Treatment of Ocular Diseases

    Ravi Sheshala and Tin Wui Wong

    20. Alginate Carriers for Bioactive Substances: Herbal Natural Compounds and Nucleic Acid Materials

    Maria Rosaria Lauro et al.


    Md Saquib Hasnain, PhD, has over six years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially in systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches as well as development and characterization of polymeric composites, formulation characterization using FTIR, DSC, PXRD, SEM, TEM, HPLC, LC-MS, and many more. He has authored many publications in various journals and book chapters, and has one Indian patent application to his credit. He has also participated and presented his research work at conferences in India and abroad. He is a member of several scientific societies, including the Royal Society of Chemistry, the International Association of Environmental and Analytical Chemistry, and the Swiss Chemical Society.


    Amit Kumar Nayak, PhD, is an Associate Professor at the Seemanta Institute of Pharmaceutical Sciences, Odisha, India. He has over ten years of research experience in the field of pharmaceutics, especially in the development and characterization of polymeric composites, hydrogels, novel and nanostructured drug delivery systems, formulation characterization using FTIR, DSC, PXRD, SEM, TEM, and HPLC. He has authored over 120 publications in various journals and has many book chapters to his credit. He has been a permanent reviewer of many international journals and has participated and presented his research work at several conferences in India. He is a life member of the Association of Pharmaceutical Teachers of India.