1st Edition
Alzheimer’s Disease Diagnosis, Molecular Targets, and Therapeutic Modalities
Chapter 1. Understanding Alzheimer's Disease: An Introduction, Pathophysiology, and Diagnosis
Avanish Tripathi and Shubham Anand
Chapter 2. Alzheimer's Disease: The Role of Blood-Brain Barrier and Strategy to Cross BBB
Hadri Hadi Md Yusof, Alina Arulsamy, and Mohmad Farooq Shaikh
Chapter 3. The Application of Vaccines in Alzheimer's Disease: Active and Passive Immunotherapies
Sreejita Chatterjee, Riya Mukherjee, Ashi Ramavat, Debjyoti Paul, and Ramendra Pati Pandey
Chapter 4. Secretase-Related Interventions in Alzheimer's: α, β, γ-Secretase, γ-Secretase Inhibitors (GSIs), γ-Secretase Modulators (GSMs) and Natural Products as GSMs
Aaditi Karnik and Abhijeet Joshi
Chapter 5. A Potential Modulator in Alzheimer's Disease : SIRT2 Inhibitors
Mushtaque A. S. Shaikh and Tamanna K. Khan
Chapter 6. Therapeutic Potential of Caspase Inhibitors in Alzheimer's Disease
Amit Sharma, Vijeta Kumari, Ripunjay Kalita, Hemant R. Jadhav, and Amritansh Bhanot
Chapter 7. Calpain Inhibitors: A Promising Therapeutic Approach in Alzheimer's Disease
Ehsan Ullah Mughal, Nafeesa Naeem, and Amina Sadiq
Chapter 8. Acetylcholinesterase Inhibitors: A Viable Therapeutic Strategy for Alzheimer's Disease
Kalpana Pandya, Devendra Kumar, Shraddha Manish Gupta, and Sushil Kumar Chaudhary
Chapter 9. Noncompetitive N-Methyl-D-Aspartate (NMDA) Antagonist for Prospective Alzheimer's Disease Treatments
Amit Sharma, Ripunjay Kalita, Hemant R. Jadhav, and Amritansh Bhanot
Chapter 10. Phosphodiesterase Inhibitors: A Promising Avenue for Modulating Cognitive Dysfunction in Alzheimer's Disease
Sylvia F. Fawzi, Daniel E. Mansour, Pierre Mansour, and Mina Y. George
Chapter 11. Autophagy Enhancer a Promising Therapeutic Approach for Alzheimer's Treatment
Prakash Haloi and Havagiray R. Chitme
Chapter 12. Therapeutic Potential of Receptor for Advanced Glycation End-Products Inhibitors in the Treatment of Alzheimer's Disease
Saikat Dewanjee and Hiranmoy Bhattacharya
Chapter 13. Targeting Alzheimer's Disease Using Neurotrophic Agents and Mimetics: Current Strategies and Challenges
Shubham Nilkanth Rahmatkar, Amit Kumar, and Damanpreet Singh
Chapter 14. Metal Chelators: A Promising Avenue for the Development of Novel Therapeutics for Alzheimer's Disease
Faisal Rehman
Chapter 15. Apolipoprotein E-Based Treatment Approach for Genetically High-Risk Alzheimer's Patients
Chanchal Mittal, Sayani Banerjee, and Sugato Banerjee
Chapter 16. Biomarkers: Diagnostic, Prognostic and Therapeutic Monitoring of Alzheimer's Disease
Amit Sharma, Ripunjay Kalita, Hemant R. Jadhav, and Amritansh Bhanot
Chapter 17. Non-Peptidic Anti-Aggregate Compounds: A Promising Avenue for Alzheimer's Disease Therapy
Akib Ali, Babita Kumari, and Pankaj Bharali
Chapter 18. Translational Potentials of Nanotechnology-Based Interventions for Alzheimer's Disease
Garima Varshney, Giriraj T Kulkarni, Mandeep Kumar Arora, Satish Kumar Gupta, Rajendra Awasthi, and Bhupesh Sharma
Chapter 19. Target of the Neurodegenerative Diseases and Mechanism of the Potent Natural Molecule
Sonima Prasad, Ankit Rathee, Geetanjali Singh, Iram Khan, Charan Singh, and Arti Singh
Chapter 20. Therapeutic Nutrition Strategies in Alzheimer's Disease
Esra Tansu Sarıyer and Meral Yüksel
Chapter 21. The Role and Importance of Exercise in Alzheimer's Disease
Dilek Özbeyli and Meral Yüksel
Biography
Devendra Kumar currently working as an Assistant Professor at School of Pharmacy & Technology Management, NMIMS University, India. He was Post-Doctoral Fellow at Department of Cellular and Integrative Physiology, University of Texas, Health Science Center, San Antonio, USA. And obtained his Ph.D from Indian Institute of Technology (Banaras Hindu University), Varanasi, India. He received Extramural Grant from Indian Council of Medical Research (ICMR, file #IIRP-2023-5582/F1, Amount of project: 39,44,085) and has written more than 45 articles published in national and international journals, 9 patents (3 granted, 6 filed), 2 book chapters. He has citations of more than 681 with h-index 15 and i10 index of 21.
Shraddha Manish Gupta has more than 15 years of research and teaching experience and currently is an Assistant Professor at School of Health Sciences and Technology, UPES, Dehradun, India. He has completed B.Pharm and M.Pharm from NDMVP’S College of Pharmacy, Nasik (M.H.) in 2003, 2006 respectively and Ph.D from Oriental University Indore, India. She Secured 96 percentile in GATE-2004 conducted by IIT, Delhi. She worked as a Research Assistant in School of Pharmacy, Monash University, Malaysia. She was Mentor in CSIR-SRTP (2020) program under Interdisciplinary Approach for Sustainable Use of Resources project-13. She has written more than 10 articles published in Q1 international journals, 2 patents (1 granted, 1published) and 8 book chapters.
Nagendra Singh Chauhan obtained his M. Pharm, Ph.D from the Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar in 2006 and 2011. He is currently working as a Senior Scientific Officer Grade-II and Government Analyst at the Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh, India. He has professional expertise in natural product isolation and phytopharmacology. He has written more than 75 articles published in national and international journals, 32 book chapters and edited five books. He has citations of more than 2700 with h-index 42 and i10 index of 38 (Google scholar) and Scopus h-index 15; 669 citations.
Kamal Shah has more than 18 years of research and teaching experience and currently working as Professor at the Institute of Pharmaceutical Research, GLA University, Mathura, India. He has completed B.Pharma from Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (M.P.) in 2003. He was gold medalist in B.Pharm., M.Pharm. from the Department of Pharmaceutical Sciences, Sagar University, Sagar, India and PhD from APJ Kalam University Lucknow, India. He has written more than 90 articles published in national and international journals, 20 book chapters and 05 edited books. His SCOPUS h index is 17, with 905 citations.
