1st Edition

American Society for Artificial Internal Organs (ASAIO) Platinum 70th Anniversary Special Edition

Edited By Pramod Bonde Copyright 2025
    470 Pages 101 Color & 229 B/W Illustrations
    by CRC Press

    This book celebrates two decades of groundbreaking research published in the ASAIO Journal, marking significant advancements in artificial organs and circulatory support.

    The American Society for Artificial Internal Organs ASAIO Platinum 70th Anniversary book is a compilation of 50 of the top papers published in the ASAIO Journal over the last two decades that have contributed to the evolution of the field. The book includes tables listing the Top 100- cited, viewed, and downloaded, articles from the ASAIO Journal. It also lists the Top 10 Altmetric Scores by Year, 2015-2024.  Topics range from artificial vision for the blind, and control systems for blood glucose, to the development of an artificial placenta IV and engineering 3D bio-artificial heart muscle, and much more.   This book represents early ideas and concepts, new treatments and devices that changed future clinical care and some early concepts that challenge the status quo. With contributions from leading experts, the ASAIO 70th Anniversary Book serves as a comprehensive resource for anyone interested in the forefront of artificial organ technology and its impact on improving patient outcomes.

    This book is intended for clinicians, scientists, engineers, and academics working for the advancement and development of innovative medical device technologies.

    1- Transcatheter Placement of an lntraluminal Prosthesis for the Thoracic Aorta

    2- Development of an Expandable Intra-aortic Prosthesis for Experimental Aortic Dissection

    3- The Potential for Neurostimulation In Obstructive Sleep Apnea

    4- Transluminal Aortic Valve Placement A Feasibility Study With a Newly Designed Collapsible Aortic Valve

    5- Improved Bioresorbable Microporous lntravascular Stents for Gene Therapy"

    6- Effects of Hemodynamics on Thromboembolism in Coronary Stents and Prototype Flow Cells In Vitro

    7- Artificial Vision for the Blind by Connecting a Television Camera to the Visual Cortex

    8- Novel Control System for Blood Glucose Using a Model Predictive Method

    9- Heparin Bonding of the Extracorporeal Circuit Reduces Thrombosis During Prolonged Lung Assist in Goats

    10- Near Infrared Spectrophotometry Reflects Cerebral Metabolism during Hypothermic Circulatory Arrest in Adults"

    11- Safety Observations in Phase I Clinical Evaluation of the Excorp Medical Bioartificial Liver Support System after the First Four Patients

    12- Development of an Implantable Artificial Anal Sphincter by the Use of the Shape Memory Alloy"

    13- Transplantation of Pig Metanephroi

    14- A Neo-Esophagus Reconstructed by Cultured Human Esophageal Epithelial Cells, Smooth Muscle Cells, Fibroblasts, and Collagen

    15- Effects of Turbulent Stresses upon Mechanical Hemolysis: Experimental and Computational Analysis

    16- Biostability of Thoralon Left Ventricular Assist Device Blood Pumping Sacs After Long-Term Clinical Use"

    17- Total Liquid Ventilation: Dynamic Airway Pressure and the Development of Expiratory Flow Limitation

    18- Future Horizons in Surgical Aortic Valve Replacement: Lessons Learned During the Early Stages of Developing a Transluminal Implantation Technique

    19- Artificial Esophagus With Peristaltic Movement

    20- Durability Testing of a Completely Implantable Electric Total Artificial Heart

    21- Development of the Human Umbilical Vein Scaffold for Cardiovascular Tissue Engineering Applications

    22- Use of a Covered Stent Modification to Produce a Transcatheter Valve: Laboratory and Animal Testing

    23- Microtextured Materials for Circulatory Support Devices: Preliminary Studies

    24- Slow Continuous Ultrafiltration with Bound Solute Dialysis

    25- Effect of Left Ventricular Assist Device Outflow Conduit Anastomosis Location on Flow Patterns in the Native Aorta

    26- Differentiated Growth of Human Renal Tubule Cells on Thin-Film and Nanostructured Materials

    27- Development of Patient-Specific Three-Dimensional Pediatric Cardiac Models

    28- Novel “Biomechanical” Polymeric Valve Prostheses with Special Design for Aortic and Mitral Position: A Future Option for Pediatric Patients?

    29- Particle Image Velocimetry–Validated, Computational Fluid Dynamics–Based Design to Reduce Shear Stress and Residence Time in Central Venous Hemodialysis Catheters

    30- Platelet Activation Due to Hemodynamic Shear Stresses: Damage Accumulation Model and Comparison to In Vitro Measurements

    31- Thin Film Nitinol Covered Stents: Design and Animal Testing

    32- Wang-Zwische Double Lumen Cannula—Toward a Percutaneous and Ambulatory Paracorporeal Artificial Lung

    33- First Experience With a Paracorporeal Artificial Lung In Humans

    34- Albumin Dialysis MARS: Knowledge from 10 Years of Clinical Investigation

    35- Design Concepts and Principle of Operation of the HeartWare Ventricular Assist System"

    36- Speed Modulation of the Continuous-Flow Total Artificial Heart to Simulate a Physiologic Arterial Pressure Waveform

    37- Effect of Alteration in Pump Speed on Pump Output and Left Ventricular Filling with Continuous-Flow Left Ventricular Assist Device

    38- A Wireless and Battery-Less Miniature Intracardiac Pressure Sensor: Early Implantation Studies

    39- Development of an Artificial Placenta IV: 24-Hour Venovenous Extracorporeal Life Support in Premature Lambs

    40- A Novel Approach to an Anatomical Adapted Stent Design for the Percutaneous Therapy of Tricuspid Valve Diseases: Preliminary Experiences From an Engineering Point of View

    41- Innovative Free-Range Resonant Electrical Energy Delivery System (FREE-D System) for a Ventricular Assist Device Using Wireless Power

    42- Hemodynamics and Flow Characteristics of a New Dialysis Port

    43- First Experience With a New Miniaturized Pump-Driven Venovenous Extracorporeal CO2 Removal System (iLA Activve): A Retrospective Data Analysis

    44- On-Line Dialysate Infusion to Estimate Absolute Blood Volume in Dialysis Patients

    45- Engineering 3D Bio-Artificial Heart Muscle: The Acellular Ventricular Extracellular Matrix Model

    46- Feasibility of Pump Speed Modulation for Restoring Vascular Pulsatility with Rotary Blood Pumps

    47- Design Rationale and Preclinical Evaluation of the HeartMate 3 Left Ventricular Assist System for Hemocompatibility

    48- FDA Benchmark Medical Device Flow Models for CFD Validation

    49- Esperanza: The First Neonatal ECMO Patient

    50- In Vitro Characterization of the Pittsburgh Pediatric Ambulatory Lung

    51- Simultaneous Venoarterial Extracorporeal Membrane Oxygenation and Percutaneous Left Ventricular Decompression Therapy with Impella Is Associated with Improved Outcomes in Refractory Cardiogenic Shock

    52- The Hemopump™, The First Intravascular Ventricular Assist Device

    53- A Proof of Concept Study, Demonstrating Extracorporeal Carbon Dioxide Removal Using Hemodialysis with a Low Bicarbonate Dialysate

    54- An Artificial Placenta Protects Against Lung Injury and Promotes Continued Lung Development in Extremely Premature Lambs

    55- The Creation of a Pediatric Health Care Learning Network: The ACTION Quality Improvement Collaborative

    56- Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019 in Shanghai, China

    57- Initial ELSO Guidance Document: ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure

    58- Telemonitoring and Care Program for Left Ventricular Assist Device Patients During COVID-19 Outbreak: A European Experience

    59- Machine Learning in Cardiac Surgery: Predicting Mortality and Readmission"


    Pramod N. Bonde, MD,  is an associate professor of cardiac surgery at Yale School of Medicine, Dr. Bonde develops and installs heart pumps to support the function of the heart and lungs. He leads a research group that includes close to a dozen physicians, engineers and student assistants, all working on developing fully implantable artificial hearts. He is the current President of the American Society for Artificial Internal Organs (ASAIO) and has been a member of the Board of Trustees since 2013.