An Introduction to Biomedical Optics: 1st Edition (Hardback) book cover

An Introduction to Biomedical Optics

1st Edition

By Robert Splinter, Brett A. Hooper

CRC Press

632 pages | 30 B/W Illus.

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pub: 2006-12-13
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Description

Many universities now offer a course in biomedical optics, but lack a textbook specifically addressing the topic. Intended to fill this gap, An Introduction to Biomedical Optics is the first comprehensive, introductory text describing both diagnostic and therapeutic optical methods in medicine. It provides the fundamental background needed for graduate students in biomedical and electrical engineering, physics, biology, and medicine to learn about several biomedical optics issues.

The textbook is divided into three main sections: general optics theory, therapeutic applications of light, and diagnostic optical methods. Each chapter has different levels of detail to build students' knowledge from one level to the next. The first section covers the history of optics theory and the basic science behind light-tissue interactions. It also introduces the relevant approaches and approximations used to describe light propagation in turbid biological media. In the second section, the authors look more closely at light-tissue interactions and their applications in different medical areas, such as wound healing and tissue welding. The final section examines the various diagnostic methods that are employed using optical techniques. Throughout the text, the authors employ numerical examples of clinical and research requirements.

Fulfilling the need for a concise biomedical optics textbook, An Introduction to Biomedical Optics addresses the theory and applications of this growing field.

Reviews

"An outstanding feature of the book is its carefully designed structure which makes it abundantly clear where required material is located . . . one should commend the high standard of production of the book; it is well laid out . . . Overall it is considered that acquisition of this book will be an excellent investment for anyone who wishes to gain an appreciation of the principles and applications of biomedical optics."

– Professor K. A. Shore, University of Wales, in Contemporary Physics, November 2007

Table of Contents

GENERAL BIOMEDICAL OPTICS THEORY

Introduction to the Use of Light for Diagnostic and Therapeutic Modalities

What Is Biomedical Optics?

Biomedical Optics Timeline

Elementary Optical Discoveries

Historical Events in Therapeutic and Diagnostic Use of Light

Light Sources

Current State of the Art

Summary

Additional Reading

Problems

Review of Optical Principles: Fundamental Electromagnetic Theory and Description of Light Sources

Definitions in Optics

Kirchhoff's Laws of Radiation

Electromagnetic Wave Theory

Light Sources

Applications of Various Lasers

Summary

Additional Reading

Problems

Review of Optical Principles: Classical Optics

Geometrical Optics

Other Optical Principles

Quantum Physics

Gaussian Optics

Summary

Additional Reading

Problems

Review of Optical Interaction Properties

Absorption and Scattering

Summary

Additional Reading

Problems

Light-Tissue Interaction Variables

Laser Variables

Tissue Variables

Light Transportation Theory

Light Propagation under Dominant Absorption

Summary

Nomenclature

Additional Reading

Problems

Light-Tissue Interaction Theory

Approximations of the Equation of Radiative Transport

Summary

Additional Reading

Problems

Numerical and Deterministic Methods in Light-Tissue Interaction Theory

Numerical Method to Solve the Equation of Radiative Transport

Measurement of Optical Parameters

Temperature Effects of Light-Tissue Interaction

Summary

Additional Reading

Problems

Light-Tissue Interaction Mechanisms and Applications: Photophysical

Range of Photophysical Mechanisms

Photoablation

Photoacoustics

Birefringence Effects

Polarization Effects

Optical Activity

Evanescent Wave Interaction in Biomedical Optics

Phase Interference Effects

Spectroscopy

Endoscopy

Summary

Additional Reading

Problems

Light-Tissue Interaction Mechanisms and Applications: Photochemical

Basic Photochemical Principles

Photochemical Effects

Summary

Additional Reading

Problems

Light-Tissue Interaction Mechanisms and Applications: Photobiological

Photobiological Biostimulation

Photobiological Effects

Excitation of Chromophores

Optic Nerve-Cell Depolarization under the Influence of Light (Vision)

Summary

Additional Reading

Problems

THERAPEUTIC APPLICATIONS OF LIGHT

Therapeutic Applications of Light: Photophysical

Delivery Considerations

Pulsed Laser Use in Cardiology

Dentistry and Oral Surgery

Ophthalmology

Optical Tweezers

Summary

Additional Reading

Problems

Therapeutic Applications of Light: Photochemical

Vascular Welding

Cosmetic Surgery

Oncology

Summary

Additional Reading

Problems

Therapeutic Applications of Light: Photobiological

Cardiology & Cardiovascular Surgery

Soft tissue Treatment

Dermatology

Fetal Surgery

Gastroenterology

General Surgery

Gynecology

Neurosurgery

Ophthalmology

Pulmonology & Otorhinolaryngology

Otolaryngology, Ear-Nose, and Throat (ENT) and Maxillofacial Surgery

Podiatry

Urology

Summary

Additional Reading

Problems

DIAGNOSTIC APPLICATIONS OF LIGHT

Diagnostic Methods Using Light: Photophysical

Optical Microscopy

Various Microscopic Techniques

Near-Field Scanning Optical Microscope

Spectroscopy

Holographic Imaging

Polarization Imaging

Transillumination Imaging

Optical Coherence Tomography

Ballistic Photon Imaging

Reflectometry

Evanescent Wave Imaging Applications

Medical Thermography

Photoacoustic Imaging

Tera Hertz Imaging

Summary

Additional Reading

Problems

Diagnostic Methods Using Light: Photochemical

Fluorescence Imaging

Ratio Fluorescence Microscopy

Raman Spectroscopy with NSOM Employed

Optical "Tongue"

Summary

Additional Reading

Problems

Diagnostic Methods Using Light: Photobiological

Immuno Staining ("Functional Imaging")

Immunofluorescence

Diagnostic Applications of Spectroscopy

Fiberoptic Sensors

Optical Coherence Tomography in Dentistry

Optical Biopsy

Determination of Blood Oxygenation

Electroluminescent Electro-Physiologic Mapping

Quantum Dots as Biological Fluorescent Markers

Compilation of the Optical Requirements for Wavelength Selection Based on the Desired Effects

Summary

Additional Reading

Problems

About the Originator

About the Series

Series in Optics and Optoelectronics

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
SCI055000
SCIENCE / Physics
TEC019000
TECHNOLOGY & ENGINEERING / Lasers & Photonics