Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened focus on select areas, Analytical Methods in Combinator
Analytical issues in combinatorial chemistry. An examination of the analytical sample resin support. Solid-phase reaction optimization using FTIR. Reaction optimization using MS and NMR methods. Reaction optimization using spectrophotometric and other methods. Quality control of combinatorial libraries. High-throughput purification. Final Thoughts and Future Perspectives.