1st Edition
Angiogenesis From Basic Science to Clinical Applications
Edited By Napoleone Ferrara
Copyright 2007
280 Pages
by
CRC Press
280 Pages
by
CRC Press
280 Pages
by
CRC Press
Also available as eBook on:
Why a new book on angiogenesis and why now? For the first time concepts proposed over 30 years ago have found clinical validation. In the last two years the first antiangiogenic agents have been approved by the FDA for the treatment of cancer and age-related macular degeneration. Not surprisingly, this clinical success has raised a new set of basic and clinical questions that need to be addressed.... Read more
Vascular Endothelial Growth Factor: Pathophysiology and Clinical Implications. Signal Transduction of VEGF Receptors toward Angiogenesis. Growth Factors and Lymphangiogenesis. Notch and Vascular Development. Neural Guidance Molecules in Vascular Development. Neuropilins, Receptors for the VEGF and Semaphorin Families, Link Angiogenesis and Axon Guidance. Non-Angiogenic Functions of VEGF. Contribution of Pro-Angiogenic Hematopoietic Cells to Vascularization of Tumor and Ischemic Tissue. Selected Antiangiogenic Drugs as Potentially Effective Universal Chemosensitizers. Using an Anti-VEGF Monoclonal Antibody to Treat Cancer. Ocular Neovascularization. Targeting VEGF for Neovascular Age-Related Macular Degeneration and Macular Edema. Therapeutic Angiogenesis for Cardiovascular Disease.
Biography
Napoleone Ferrara
