Animal Cell Technology: From Biopharmaceuticals to Gene Therapy, 1st Edition (Hardback) book cover

Animal Cell Technology

From Biopharmaceuticals to Gene Therapy, 1st Edition

Edited by Leda Castilho, Angela Moraes, Elisabeth Augusto, Mike Butler

Taylor & Francis

506 pages | 129 B/W Illus.

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Hardback: 9780415423045
pub: 2007-12-13
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Animal Cell Technology: from Biopharmaceuticals to Gene Therapy provides a comprehensive insight into biological and engineering concepts related to mammalian and insect cell technology, as well as an overview of the applications of animal cell technology. Part 1 of the book covers the Fundamentals upon which this technology is based and covers the science underpinning the technology. Part 2 covers the Applications from the production of therapeutic proteins to gene therapy. The authors of the chapters are internationally-recognized in the field of animal cell culture research and have extensive experience in the areas covered in their respective chapters.


"…an excellent introduction to all aspects of animal cell culture."

Biotechnology Advances

Table of Contents

1. Introduction to Animal Cell Technology

2. Animal Cells: Basic Concepts

3. Cloning and Expression of Heterologous Proteins in Animal Cells

4. Cell Metabolism and its Control in Culture

5. Culture Media for Animal Cells

6. Post-Translational Modification of Recombinant Proteins

7. Mechanisms of Cell Proliferation and Cell Death in Animal Cell Culture In Vitro

8. Mathematical Models for Growth and Product Synthesis in Animal Cell Culture

9. Bioreactors for Animal Cells

10. Monitoring and Control of Cell Cultures

11. Animal Cell Separation

12. Product Purification Processes

13. Quality Control of Biotechnological Products

14. Regulatory Aspects

15. Intellectual Property

16. Recombinant Therapeutic Proteins

17. Monoclonal Antibodies

18. Viral Vaccines: Concepts, Principles and Bioprocesses

19. Bioinsecticides

20. Cell Therapies and Stem Cells

21. Gene Therapy

About the Editors

Leda R. Castilho - Cell Culture Engineering Laboratory, Chemical Engineering Program - CPPE, Federal University of Rio do Janeiro, Brazil

Angela Maria Moraes - School of Chemical Engineering, Department of Biotechnological Processes, State University of Campinas, Brazil

Elisabeth F. P. Augusto - Institute of Technological Research of the State of Sao Paulo, Brazil

Michael Butler - Department of Microbiology, University of Manitoba, Canada

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
SCIENCE / Life Sciences / Biology / General
SCIENCE / Biotechnology
SCIENCE / Life Sciences / Genetics & Genomics
SCIENCE / Life Sciences / General