Anti-AIDS Drug Development  book cover
1st Edition

Anti-AIDS Drug Development

ISBN 9783718656981
Published March 1, 1995 by CRC Press
304 Pages

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Book Description

This book covers the major arenas of drug development, providing understanding of the pros and cons of the various efforts of chemists and biologists to explore newer antiviral targets for HIV replication and to look for and design molecules that will have minimal toxicities.

Table of Contents

1. From Anti-HIV Agents to Anti-AIDS Chemotherapy: A Critical Appraisal 2. Nucleosides and Derivatives 3. Iminosugar a-Glucosidase Inhibitors 4. Inhibition of HIV Protease: A Strategy for the Treatment of AIDS 5. Regulatory Proteins of Hum an Immunodeficiency 6. CD4 Mimetics and Analogs 7. Antisense Oligonucleotide Approach for Therapy of AIDS 8. Resistance to Anti-HIV Agents for Anti-AIDS Drug Development 9. Anti-HIV Drug Test Systems: Significance and Limitations 10. Plant-derived Anti-HIV Agents 11. HIV-1-specific Reverse Transcriptase Inhibitors 12. Small and Large Polyanionic Derivatives

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Mohan, Prem; Masanori, Baba