1st Edition

Antibiotic Optimization Concepts and Strategies in Clinical Practice

    This book focuses on topics ranging from the economics of drug-resistant infections and the management of antimicrobial use to new information on methods to optimize the selection, route of administration, dosing, and duration of antimicrobial therapies for common infections. In addition to offering ideas on studied programmatic approaches for judicious utilization of antimicrobial agents, this reference discusses practical means to track intervention outcomes through benchmarking. Authored by experts in their respective fields, the book contains essential principles and practical strategies to optimize the utility of antimicrobial agents in modern inpatient health care settings.

    Concepts, Principles, and Rationale for Optimizing the Institutional Use of Antimicrobial Agents; How to Create a Therapeutics Committee That is Scientifically and Economically Sound Richard Quintiliani and Robert Quercia; The Public Health Action Plan to Combat Antimicrobial Resistance and the Prevention of Antimicrobial Resistance in Healthcare Settings J. Todd Weber; Why Appropriate Antibiotic Selection is Important: Focus on Outcomes Marin H. Kollef; Role of Microbiologic Surveillance Data in Selecting Optimal Antimicrobial Therapy Mike Dudley; Antimicrobial Pharmacodynamics for the Clinician David Andes and Bill Craig; Role of Adverse Events and Medical Errors in the Formulary Decision Process David Nix; Basic Pharmacoeconomics for the Hospital Decision Maker Mary Anne McCollum; Applied Strategies, Programs, and Guidelines: Optimizing the Institutional Use of Antimicrobial Agents; The Role of Infection Control and Hospital Epidemiology in the Optimization of Antibiotic Use August J. Valenti; Antimicrobial Stewardship Initiatives: A Programmatic Approach to Optimizing Antimicrobial Use Gilles Fraser, Patricia Stogsdill, and Robert C. Owens, Jr.; Role of Computer-Assisted Programs in Optimizing the Use of Antimicrobial Agents John Burke; Application of Pharmacodynamic Principles: From Theory to Practice Joseph L. Kuti and David Nicolau; Impacting Institutional Antimicrobial Use: Focus on Resistance Profiles and Bug-Drug Specific Relationships Robert C. Owens, Jr. and Paul G. Ambrose; Early Discharge Strategies: Role of Transitional Therapy Programs Julio Ramirez.

    Biography

    Robert C. Owens, Charles H. Nightingale, Paul G. Ambrose

    " The editors are to be congratulated for assembling an expert group of authors to write the 19 chapters that make up this treatise….a good resource by which to ensure the appropriate use of antimicrobial therapy."
    -New England Journal of Medicine