1st Edition
Antidiabetic Potential of Plants in the Era of Omics
Here is an informative overview of diabetes mellitus in conjunction with plant-based treatments. It discusses available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches.
The book begins with an introduction to diabetes, giving a brief overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with ethnobotanical information. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects of active plantbased antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques.
PART I: INTRODUCTION TO DIABETES
1. Diabetes Mellitus: History, Diagnosis, Classification, Pathophysiology, Risk Factors
Younis Ahmad Hajam, Javid Ahmad Malik, Deepu Pandita, and Raksha Rani
2. Diabetes Mellitus: Signs and Symptoms, Epidemiology, Current Prevention, and Management Therapies and Treatments
Younis Ahmad Hajam, Raksha Rani, Javid Ahmad Malik, Anu Pandita, Riya Sharma, and Rajesh Kumar
PART II: ANTIDIABETIC PLANTS IN SYSTEMS OF TRADITIONAL KNOWLEDGE
3. The "Green Healers" of Diabetes Mellitus: An Ayurvedic Eye
Arun Bhanu K and Lavanya Mohan
4. Concept of Diabetes Mellitus and Antidiabetic Plants in the Unani System of Medicine
Ahmad Ali and Nikhat Shaikh
5. Omics Technology in Antidiabetic Plant Research
Seema Singh, Charanjit Singh, and Abdul Hadi
6. Ethnobotanical Information of Medicinal Plants Used for Diabetes Mellitus in the Seshachalam Biosphere Reserve, Andhra Pradesh, India
A. Madhusudhana Reddy and C. Nagendra
PART III: MODES OF ACTION
7. Overview of Steviol Glycosides: Action toward Diabetes Control
Payal Agarwal, Renitta Jobby, and Pamela Jha
8. Mechanism of Action of the Traditional and Modern Phyto-Biotics in the Treatment of Diabetes in the Current Era
K. Venkata Ratnam, Lepakshi Md. Bhakshu, and R. R. Venkata Raju
9. Molecular Insights of Active Plant-Based Antidiabetic Drug Molecules
Pravallika, B. S. Supreetha, V. Veena, J. Selvakumar, and Harikrishnan
PART IV: RECENT BIOTECHNOLOGICAL ADVANCEMENTS OF ANTIDIABETIC PLANTS AND PLANT-BASED ANTIDIABETES DRUGS AND FUTURE PERSPECTIVES WITH GENOME EDITING TECHNOLOGIES
10. Molecular Breeding and Application of Molecular Markers for Improvement of Antidiabetic Medicinal Plants
Sameena Shaik, Anand Kumar, Gunti Mallikarjuna, Guru Lakshmi Kola, P. Chandra Obul Reddy, and A. Chandra Sekhar
11. Biotechnologically Engineered Transgenic Medicinal Plants: Exploration of Antidiabetic Properties
Priya Sundarrajan and Lekha Bhagtaney
12. Transcriptomic Studies of Medicinal Plants Elucidating Their Role in Diabetes
Rohit Kumar, Lata Sharma, and Neelesh Kapoor
13. How Metabolomics Shapes the Future of Drugs in Antidiabetic Plants
Javid Ahmad Malik, Shaza Hussiny Aly, Younis Ahmad Hajam, and Sameer Quazi
14. Zinc Finger Nuclease Based Genome Editing in Enhancement of Antidiabetic Activity of Plants: Prospective Applications
Parama Majumdar, Geetanjali Harale, Suman Ganger, and Sheetal Pardeshi
15. Transcription Activator-Like Effector Nucleases (Talens): A Genome Editing Tool to Explore Enhanced Activity of Antidiabetic Plants
Geetanjali Harale, Sheetal Pardeshi, Parama Majumdar, and Suman Ganger
Biography
Deepu Pandita
The quality of the book is well-done and it is organized in a way that will enable a variety of practitioners to utilize the material. The background and
use of many contributors is exceptional, and the research and dedication are apparent in this publication. - Amy Schreiner, DC, DICCP v(Northwestern Health Sciences University)
